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CAY10416

CAY10416 Struktur
443919-96-8
CAS-Nr.
443919-96-8
Englisch Name:
CAY10416
Synonyma:
CAY10416;CAY10416,CAY-10416;3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole;1H-Pyrazole, 3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-
CBNumber:
CB72590410
Summenformel:
C29H29FN2O5S
Molgewicht:
536.61
MOL-Datei:
443919-96-8.mol

CAY10416 Eigenschaften

storage temp. 
Store at -20°C
L?slichkeit
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 5 mg/ml
Aggregatzustand
A crystalline solid

Sicherheit

CAY10416 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Dual cyclooxygenase-2 (COX-2)/5-lipoxygenase (5-LO) inhibitors are potential therapeutic agents for inflammatory diseases and for prostate cancer. CAY10416 is a dual COX-2/5-LO inhibitor with IC50 values of 50 and 3 nM, respectively. The selectivity of CAY10416 for COX is greater than 200-fold for COX-2 versus COX-1. COX-2/5-LO inhibitors such as CAY10416 are also apoptosis-inducing agents and are potentially useful in prostate cancer chemotherapy. In the PC3 human carcinoma cell line, CAY10416 exhibits a 45% inhibition of proliferation at 100 μM. In the LNCaP human carcinoma cell line, CAY10416 inhibits growth with an IC50 value of 83 μM.

CAY10416 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


CAY10416 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 22)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11218 58
Energy Chemical 021-58432009 400-005-6266
marketing@energy-chemical.com China 44918 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24644 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337
3427709316@qq.com China 7979 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
customer_service@efebio.com China 11974 58

  • CAY10416
  • 3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole
  • 1H-Pyrazole, 3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-
  • CAY10416,CAY-10416
  • 443919-96-8
  • C29H29FN2O5S
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