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Begacestat

Begacestat Struktur
769169-27-9
CAS-Nr.
769169-27-9
Englisch Name:
Begacestat
Synonyma:
GSI-953;Begacestat;Begacestat(GSI-953);GSI-953 DISCONTINUED;Begacestat (Synonyms: GSI-953);5-Chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxyMethyl)-2-(trifluoroMethyl)propyl]-2-thiophenesulfonaMide;2-Thiophenesulfonamide, 5-chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxymethyl)-2-(trifluoromethyl)propyl]-;5-Chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxymethyl)-2- (trifluoromethyl)propyl] thiophene-2-sulfonamide;(2S)-S-(5-chlorothiophen-2-yl)-4,4,4-trifluoro-1-hydroxy-N-Methyl-3-(trifluoroMethyl)butane-2-sulfonaMido
CBNumber:
CB72535664
Summenformel:
C9H8ClF6NO3S2
Molgewicht:
391.74
MOL-Datei:
769169-27-9.mol

Begacestat Eigenschaften

Schmelzpunkt:
153-155°C
Siedepunkt:
355℃
Dichte
1.642
Flammpunkt:
169℃
storage temp. 
2-8°C
L?slichkeit
DMSO: ≥15mg/mL
Aggregatzustand
powder
pka
8.16±0.50(Predicted)
Farbe
white to tan

Sicherheit

WGK Germany  3

Begacestat Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Begacestat (GSI-953) is a selective β-secretase inhibitor that selectively inhibits cleavage of APP over Notch. GSI-953 is used for treating diseases such as cancer in relation to prevention of intestinal secretory metaplasia.

Begacestat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Begacestat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 57)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49734 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
 jkinfo@jkchemical.com China 96815 76
Chemsky (shanghai) International Co.,Ltd 021-50135380
shchemsky@sina.com China 15402 60
shanghai cooperpharm co.,LTD . +86-021-58975553
sales@cooperpharm.com China 1210 56
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396
 sales@chem-strong.com China 18070 56
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9806 58
Shanghai BetterBioChem Co., Ltd. +86-18017644823
sales@betterbiochem.com China 325 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684;
 sales@rrkchem.com China 57423 58
  • Begacestat
  • Begacestat(GSI-953)
  • GSI-953
  • 5-Chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxyMethyl)-2-(trifluoroMethyl)propyl]-2-thiophenesulfonaMide
  • (2S)-S-(5-chlorothiophen-2-yl)-4,4,4-trifluoro-1-hydroxy-N-Methyl-3-(trifluoroMethyl)butane-2-sulfonaMido
  • 5-Chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxymethyl)-2- (trifluoromethyl)propyl] thiophene-2-sulfonamide
  • 2-Thiophenesulfonamide, 5-chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxymethyl)-2-(trifluoromethyl)propyl]-
  • Begacestat (Synonyms: GSI-953)
  • GSI-953 DISCONTINUED
  • 769169-27-9
  • C9H8ClF6NO3S2
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pfizer Compounds
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
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