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Hh-Ag 1.3

Hh-Ag 1.3 Struktur
364590-63-6
CAS-Nr.
364590-63-6
Englisch Name:
Hh-Ag 1.3
Synonyma:
Hh-Ag 1.3;Smoothened Agonist, HCl;Frizzled6 agonist SAG1.3;SAG . dihydrochloride (water soluble);3-Chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiophene-2-carboxamide;Benzo[b]thiophene-2-carboxamide, 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-;3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide,hydrate,dihydrochloride
CBNumber:
CB72524538
Summenformel:
C28H28ClN3OS
Molgewicht:
490.06
MOL-Datei:
364590-63-6.mol

Hh-Ag 1.3 Eigenschaften

Siedepunkt:
688.6±55.0 °C(Predicted)
Dichte
1.30±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
DMSO: 10mg/mL
water: 25mg/mL
Aggregatzustand
White to off-white solid.
pka
10?+-.0.40(Predicted)
Farbe
light yellow
Wasserl?slichkeit
Soluble in water.
Sensitive 
Light Sensitive & Hygroscopic

Sicherheit

Hh-Ag 1.3 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Smoothened Agonist, HCl (SAG), is a highly potent activator of Smo (smoothened). This chlorobenzothiophene compound is a hedgehog pathway agonist that interacts with the heptahelical domain of Smo. SAG is shown to act as an activator at low concentrations, but can inhibit Smo coupling at very high concentrations. The activating effects of SAG will counteract Cyclopamine or Cyclopamine-KAAD inhibition of Smo.

Hh-Ag 1.3 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Hh-Ag 1.3 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 14)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
Shanghai Witofly Chemical Co.,Ltd
sales@witofly.com China 2864 52
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396
 sales@chem-strong.com China 18067 56
Aikon International Limited 025-58851090 13611564524
 lwan@aikonchem.com China 15951 58
Nanjing crow LuNing pharmaceutical technology co., LTD 13382066392
CHINA 4877 58
Energy Chemical 021-58432009 400-005-6266
 marketing@energy-chemical.com China 44918 58
Nantong Hanfang Biotechnology Co. , Ltd. 18616537568
 hanfangpharma@126.com China 29981 58

364590-63-6()Verwandte Suche:

  • 3-Chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiophene-2-carboxamide
  • Smoothened Agonist, HCl
  • SAG . dihydrochloride (water soluble)
  • Hh-Ag 1.3
  • 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide,hydrate,dihydrochloride
  • Benzo[b]thiophene-2-carboxamide, 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-
  • Frizzled6 agonist SAG1.3
  • 364590-63-6
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