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1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE

1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Struktur
100991-92-2
CAS-Nr.
100991-92-2
Englisch Name:
1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE
Synonyma:
1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE;2-Hydroxymethyl-3,4-pyrrolidinediol hydrochloride;1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride enzyme inhibitor;3,4-Pyrrolidinediol, 2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R)-;(2R,3R,4R)-3,4-Dihydroxy-2-(hydroxymethyl)pyrrolidine hydrochloride
CBNumber:
CB7230309
Summenformel:
C5H12ClNO3
Molgewicht:
169.61
MOL-Datei:
Mol file

1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Eigenschaften

Schmelzpunkt:
110-112 °C(Solv: ethyl ether (60-29-7); methanol (67-56-1))
storage temp. 
2-8°C
L?slichkeit
DMSO: 10 mg/ml; PBS (pH 7.2): 1 mg/ml
Aggregatzustand
A crystalline solid

Sicherheit

WGK Germany  3

1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

1,4-dideoxy-1,4-imino-D-Arabinitol (DAB) is an inhibitor of glycogen phosphorylase, a key enzyme in glycogenolysis. It inhibits glycogenolysis in isolated liver cells (IC50 = 1.0 μM) and in homogenates of cerebral cortex and cerebellum (IC50s = 463 and 383 nM, respectively). DAB is used to inhibit glycogenolysis, in liver and in brain, in various animal models.

Verwenden

1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride has been used as an α-glucosidase (GAA) inhibitor.

Allgemeine Beschreibung

1,4-Dideoxy-1,4-imino-D-arabinitol is a naturally occurring pyrrolidine alkaloid. It is found in Arachniodes standishii and Angylocalyx boutiqueanus.

1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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100991-92-2()Verwandte Suche:

  • 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE
  • 2-Hydroxymethyl-3,4-pyrrolidinediol hydrochloride
  • (2R,3R,4R)-3,4-Dihydroxy-2-(hydroxymethyl)pyrrolidine hydrochloride
  • 1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride enzyme inhibitor
  • 3,4-Pyrrolidinediol, 2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R)-
  • 100991-92-2
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