Anti-phospho-DARPP32 (pThr75) antibody produced in rabbit Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-phospho-DARPP32 (pThr75) antibody produced in rabbit is suitable for dot blot and western blot analysis at a working dilution of 1:1000 using rat caudate lysates.
Allgemeine Beschreibung
DARPP32 is a phosphoprotein with a molecular mass of 32kDa. It is regulated by dopamine (DA) and cAMP and is associated with dopaminoceptive neurons bearing D-1 receptors in the basal ganglia. DARPP32 is a target for the actions of dopamine.
Biochem/physiol Actions
Dopamine D1 receptor stimulation enhances cAMP formation, resulting in the phosphorylation of DARPP32. Phosphorylation of DARPP32 plays an important role in the regulation of dopaminergic neurotransmission. The activity of this protein has an important role in the actions of alcohol, caffeine and Prozac?.
Anti-phospho-DARPP32 (pThr75) antibody produced in rabbit Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
