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GMDP

GMDP Struktur
70280-03-4
CAS-Nr.
70280-03-4
Englisch Name:
GMDP
Synonyma:
GMDP;syl)muramoyl)-l-alanyl-;glucosaminylmuramyldipeptide;4-(2-ACETAMIDO-2-DEOXY-B-D- &;4-(2-acetamido-2-deoxy-B-D-*glucopyranosyl)-N-ace;d-glcnac-β-(1→4)-n-acetylmuramyl-l-ala-d-isoglutamine;D-GLCNAC-BETA-(1->4)-N-ACETYLMURAMYL-L-ALA-D-ISOGLUTAMINE;N-Acetyl-D-glucosaminyl-(b1,4)-N-acetylmuramyl-L-alanyl-D-io;n-acetylglucosaminyl-n-acetylmuramyl-l-alanyl-d-isoglutamine;n-acetyl-beta-glucosaminyl-n-acetylmuramyl-alanylisoglutamine
CBNumber:
CB7201998
Summenformel:
C27H45N5O16
Molgewicht:
695.67
MOL-Datei:
70280-03-4.mol

GMDP Eigenschaften

storage temp. 
−20°C

Sicherheit

Kennzeichnung gef?hrlicher Xn
R-S?tze: 20/21/22
S-S?tze: 36/37
WGK Germany  3
RTECS-Nr. MA2275230

GMDP Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

N-acetyl-β-D-glucosaminyl-( 1→4)-N-acetylmuramyl-L-alanyl-D-isoglutamine was launched in Russia for hospital-related infections, psoriasis, cervical precancerous lesions and ophthalmic keratitis caused by herpes. It was found to be less pyrogenic than MDP, the minimally active component of Freund's complete adjuvant. While chemical synthesis is possible, a less laborious method (3 steps) involves the enzymatic degradation of a bacterial peptidoglycan. GDMP is orally active with a low toxicity that acts as an adjuvant to highly purified protein antigens to stimulate the induction of CD8* T-cell response. It was also able to reduce the levels of TNF-α, IL-1α and hypoglycemia induced by LPS administration and to inhibit systemic response to endotoxin.

Originator

Peptech (Australia)

Trademarks

Likopid

GMDP Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

GMDP Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 10)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396
 sales@chem-strong.com China 18146 56
Nanjing Peptide Biotech Ltd. 025-025-58361106-805-805 13082558573
 liugang@njpeptide.com China 9980 55
Nantong Hanfang Biotechnology Co. , Ltd. hanfangpharma@126.com; 18616537568
 hanfangpharma@126.com China 29981 58
Changzhou Xianglong Pharmaceutical Technology Co., Ltd., 18915873328 18915873328
 296197970@qq.com China 11055 58

70280-03-4()Verwandte Suche:

  • d-alpha-glutamine,n-(n-acetyl-4-o-(2-(acetylamino)-2-deoxy-beta-d-glucopyrano
  • glucosaminylmuramyldipeptide
  • n-acetyl-beta-glucosaminyl-(1-4)-n-acetylmuramyl-l-alanyl-d-isoglutamine
  • n-acetyl-beta-glucosaminyl-n-acetylmuramyl-alanylisoglutamine
  • n-acetylglucosaminyl-n-acetylmuramyl-l-alanyl-d-isoglutamine
  • syl)muramoyl)-l-alanyl-
  • 4-(2-acetamido-2-deoxy-B-D-*glucopyranosyl)-N-ace
  • N-Acetyl-D-glucosaminyl-(b1,4)-N-acetylmuramyl-L-alanyl-D-io
  • 4-(2-ACETAMIDO-2-DEOXY-B-D- &
  • 4-(2-acetamido-2-deoxy-β-d-glucopyranosyl)-n-acetylmuramyl-l-ala-d-glu amide
  • d-glcnac-β-(1→4)-n-acetylmuramyl-l-ala-d-isoglutamine
  • D-GLCNAC-BETA-(1->4)-N-ACETYLMURAMYL-L-ALA-D-ISOGLUTAMINE
  • GMDP
  • N-ACETYL-D-GLUCOSAMINYL-(BETA1,4)-N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE
  • 4-(2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSYL)-N-ACETYLMURAMYL-L-ALA-D-GLU AMIDE
  • N-Acetyl-beta-D-Glucosaminyl-N-Acetylmuramyl-L-Alanyl-D-Isoglutamine
  • D-α-Glutamine, N-[N-acetyl-4-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]muramoyl]-L-alanyl-
  • (4R)-4-((2S)-2-((2R)-2-(((3R,4R,5S,6R)-3-acetamido-5-(((2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)propanamido)propanamido)-5-amino-5-oxopentanoic acid
  • N-?Acetyl-?β-?D-?glucosaminyl-?N-?acetylmuramyl-?L-?alanyl-?D-?isoglutamine
  • 70280-03-4
  • C27H45N5O16
  • Dipeptides and Tripeptides
  • Dipeptides
  • BioChemical
  • Amino Acids and Peptides
  • Biochemicals and Reagents
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