4-Methoxy-N,N'-bis(3-pyridylmethyl)isophthaldiamid
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- CAS-Nr.
- 32828-81-2
- Bezeichnung:
- 4-Methoxy-N,N'-bis(3-pyridylmethyl)isophthaldiamid
- Englisch Name:
- Picotamide
- Synonyma:
- g137;PICOTAMIDE;N,N’-Bis(3-Pyridinylmethyl)-4-Me;n,n’-bis(3-picolyl)-4-methoxyisophthalamide;4-methoxy-n,n’-bis(3-pyridylmethyl)isophthalamide;4-methoxy-n,n’-bis(3-pyridylmethyl)-isophthalamid;4-methoxy-N,N'-bis(3-pyridylmethyl)isophthaldiamide;Isophthalamide, 4-methoxy-N,N'-bis(3-pyridylmethyl)-;4-Methoxy-N1,N3-bis(pyridin-3-ylmethyl)isophthalamide;n,n’-bis(3-pyridinylmethyl)-4-methoxy-3-benzenedicarboxamide
- CBNumber:
- CB7167904
- Summenformel:
- C21H20N4O3
- Molgewicht:
- 376.41
- MOL-Datei:
- 32828-81-2.mol
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4-Methoxy-N,N'-bis(3-pyridylmethyl)isophthaldiamid Eigenschaften
- Schmelzpunkt:
- 128-131℃
- Siedepunkt:
- 668.1±55.0 °C(Predicted)
- Dichte
- 1.246±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- L?slichkeit
- Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
- pka
- 13.31±0.46(Predicted)
- Aggregatzustand
- White solid.
- Farbe
- White
- Stabilit?t:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
2 |
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| RTECS-Nr. |
CZ2235500 |
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| Toxizit?t |
LD50 i.p. in male mice: 1205 mg/kg (Orzalesi, Selleri, 1976) |
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| Bildanzeige (GHS) |
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| Alarmwort |
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H303 |
May be harmfulif swallowed |
Acute toxicity,oral |
Category 5 |
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P312 |
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| Sicherheit |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P403 |
An einem gut belüfteten Ort aufbewahren. |
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4-Methoxy-N,N'-bis(3-pyridylmethyl)isophthaldiamid Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Picotamide is an unique antithrombotic agent which acts by selectively inhibiting
thromboxane synthesis and blocking platelet thromboxane receptors without affecting
prostaglandin synthesis. It is reported to be useful in the treatment of myocardial
infarction, cerebrovascular disorders, pulmonary embolism and atherosclerosis.
Verwenden
Picotamide is a dual inhibitor of thromboxane A2 and thromboxane A2 synthase. It is used in aptamers for targeting coagulation factor XIII and there used for treatment of thrombosis.
4-Methoxy-N,N'-bis(3-pyridylmethyl)isophthaldiamid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-Methoxy-N,N'-bis(3-pyridylmethyl)isophthaldiamid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 57)Lieferanten
32828-81-2(4-Methoxy-N,N'-bis(3-pyridylmethyl)isophthaldiamid)Verwandte Suche:
- 4-METHOXY-N,N'-BIS(3-PYRIDINYLMETHYL)-1,3-BENZENEDICARBOXAMIDE
- PICOTAMIDE
- 4-methoxy-n,n’-bis(3-pyridylmethyl)-isophthalamid
- 4-methoxy-n,n’-bis(3-pyridylmethyl)isophthalamide
- g137
- n,n’-bis(3-picolyl)-4-methoxyisophthalamide
- n,n’-bis(3-pyridinylmethyl)-4-methoxy-1,3-benzenedicarboxamide
- n,n’-bis(3-pyridinylmethyl)-4-methoxy-3-benzenedicarboxamide
- 4-methoxy-N,N'-bis(3-pyridylmethyl)isophthaldiamide
- -1,3-Benzenedicarboxamide, N,N'-bis(3-pyridinylmethyl)-4-methoxy
- Isophthalamide, 4-methoxy-N,N'-bis(3-pyridylmethyl)-
- N,N’-Bis(3-Pyridinylmethyl)-4-Me
- 4-methoxy-1-N,3-N-bis(pyridin-3-ylmethyl)benzene-1,3-dicarboxamide
- 1,3-Benzenedicarboxamide, 4-methoxy-N1,N3-bis(3-pyridinylmethyl)-
- inhibit,Picotamide,Inhibitor,Prostaglandin Receptor,Antiplatelet,Microalbuminuria,Carotid plaques
- 4-Methoxy-N1,N3-bis(pyridin-3-ylmethyl)isophthalamide
- 4-Methoxy-N,N'-bis(3-pyridinylmethyl)-1,3-benzenedicarboxamide
- 32828-81-2
- C21H20N4O3H2O
- C21H20N4O3
- Enzymes, Inhibitors, and Substrates
- Enzyme Inhibitors
- Enzyme Inhibitors by Enzyme
- Thromboxane synthase
- R to Z
- BioChemical
- Biochemicals and Reagents
