Isobutylchlorformiat Chemische Eigenschaften,Einsatz,Produktion Methoden
ERSCHEINUNGSBILD
FARBLOSE FLüSSIGKEIT MIT STECHENDEM GERUCH.
CHEMISCHE GEFAHREN
Zersetzung beim Verbrennen unter Bildung giftiger und ?tzender Rauche. Reagiert mit Wasser oder Feuchtigkeit unter Bildung von Chlorwasserstoff.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).
MAK: 0.2 ppm, 1.1 mg/m? Spitzenbegrenzung: überschreitungsfaktor I(2); Schwangerschaft: Gruppe C; (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den K?rper durch Inhalation der D?mpfe und durch Verschlucken.
INHALATIONSGEFAHREN
Beim Verdampfen bei 20°C tritt sehr schnell eine gesundheitssch?dliche Kontamination der Luft ein.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION: Die Substanz ver?tzt die Augen, die Haut und die Atemwege. ?tzend beim Verschlucken. Inhalation des Dampfes kann zu Lungen?dem führen (s. Anm.). Die Auswirkungen treten u.U. verz?gert ein.
LECKAGE
Gefahrenbereich verlassen! Fachmann zu Rate ziehen! Pers?nliche Schutzausrüstung: Chemikalienschutzanzug mit umgebungsluftunabh?ngigem Atemschutzger?t. NICHT in die Umwelt gelangen lassen. Ausgelaufene Flüssigkeit in abdichtbaren, trockenen Kunststoffbeh?ltern sammeln. Reste mit trockenem Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen.
R-S?tze Betriebsanweisung:
R10:Entzündlich.
R22:Gesundheitssch?dlich beim Verschlucken.
R23:Giftig beim Einatmen.
R34:Verursacht Ver?tzungen.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
Chemische Eigenschaften
clear liquid
Verwenden
Isobutyl chloroformate is used as a peptide reagent. It is also used in the preparation of phenethyl-carbamic acid isobutyl ester by reaction with phenethylamine.
Allgemeine Beschreibung
A colorless to light-colored liquid. Insoluble in water and denser than water. Very corrosive to skin, eyes, and mucous membranes. Very toxic by ingestion, inhalation and skin absorption. Combustible.
Air & Water Reaktionen
Highly flammable. Insoluble in water. Reacts with moisture in the air to produce highly corrosive and toxic fumes of hydrogen chloride gas. Decomposes exothermically in water.
Reaktivit?t anzeigen
Isobutyl chloroformate is incompatible with water, with strong oxidizing agents, alcohols, bases (including amines). May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
Hazard
Flammable. Corrosive.
Health Hazard
TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Bromoacetates and chloroacetates are extremely irritating/lachrymators. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Brandgefahr
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.
m?gliche Exposition
This is a high volume chemical
with production exceeding 1 million pounds annually in the
U.S . No specific use found
Versand/Shipping
UN2742 Chloroformates, toxic, corrosive, flammable, n.o.s., Hazard class: 6.1; Labels: 6.1—Poison
Inhalation Hazard, 8—Corrosive material; 3—Flammable
liquid; Technical Name Required, Potential Inhalation
Hazard (Special Provision 5). PG II. UN3390 Toxic
by inhalation liquid, corrosive, n.o.s. with an LC50
# 1000 mL/m3 and saturated vapor concentration ≥ 10
LC50, Hazard Class: 6.1; Labels: 6.1—Poisonous materials,
8—Corrosive material, Technical Name Required,
Inhalation Hazard Zone B
l?uterung methode
It can be dried over CaCl2 and fractionated at atmospheric pressure while keeping moisture out. Its purity can be checked by conversion to the phenyl urethane derivative with PhNCO [Saunders et al. J Am Chem Soc 73 3796 1951.] IR: 1780cm-1 [Thompson & Jameson Spectrochim Acta 13 236 1959, R.se JustusLiebigs Ann Chem 205 227 1880]. [Beilstein 3 IV 26.]
Inkompatibilit?ten
Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides, alcohols, ethers, amines.
Forms explosive mixture with air above flash point
(27C). Compounds of the carboxyl group react with all
bases, both inorganic and organic (i.e., amines) releasing
substantial heat, water and a salt that may be harmful.
Incompatible with arsenic compounds (releases hydrogen
cyanide gas), diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides (releasing heat,
toxic and possibly flammable gases), thiosulfates and
dithionites (releasing hydrogen sulfate and oxides of sulfur). Decomposes exothermically in water. Reacts with
moisture in air to produce highly corrosive and toxic
fumes of hydrogen chloride gas
Waste disposal
Disposal of unused product
must be undertaken by qualified personnel who are knowledgeable in all applicable regulations and follow all pertinent safety precautions including the use of appropriate
protective equipment. For proper handling and disposal,
always comply with federal, state, and local regulations.
Isobutylchlorformiat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte