4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene
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- CAS-Nr.
- 461432-23-5
- Englisch Name:
- 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene
- Synonyma:
- 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene;Dapagliflozin Bromo impurity;Benzene, 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]-;Dapagliflozin-13;Dapaglifozin DAP Bromo;5-broMo-2-chloro-4’Dapagliflozin Impurity 15;4-(Dibenzofuranyl)boronic;Dapagliflozin Impurity 82;Dapagliflozin Intermediate 1
- CBNumber:
- CB71456759
- Summenformel:
- C15H14BrClO
- Molgewicht:
- 325.63
- MOL-Datei:
- 461432-23-5.mol
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4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Eigenschaften
- Siedepunkt:
- 393.0±32.0 °C(Predicted)
- Dichte
- 1.371±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Low-Melting Solid
- Farbe
- White to Off-White
- Stabilit?t:
- Stable under recommended storage conditions., Stable Under Recommended Storage C
- InChI
- InChI=1S/C15H14BrClO/c1-2-18-14-6-3-11(4-7-14)9-12-10-13(16)5-8-15(12)17/h3-8,10H,2,9H2,1H3
- InChIKey
- ZUNCHZBITMUSRD-UHFFFAOYSA-N
- SMILES
- C1(Cl)=CC=C(Br)C=C1CC1=CC=C(OCC)C=C1
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
5-Bromo-2-chloro-4'-ethoxydiphenylmethane is a hydrocarbon derivative and can be used as an intermediate for dapagliflozin.
Synthese
Oxalyl chloride (0.8 mL) was added to a solution of 5-bromo-2-chlorobenzoic acid (2 g) in dichloromethane (20 mL) and dimethylformamide (0.2 mL) under a nitrogen atmosphere. The reaction mixture was stirred for one hour at 25° C to 30° C. After completion of the reaction, the reaction mixture was concentrated under a vacuum at 40° C to 45° C. to obtain an oily residue. The oily residue was dissolved in dichloromethane (20 mL) and cooled to 0° C. To this solution, phenol (1.1 mL) and aluminium chloride (2.3 g) were added at 0° C. to 5° C. The reaction mixture was stirred at 0° C to 5° C for 2 hours. The reaction mixture was allowed to warm to about 20° C, and triethylsilane (3.4 mL) was slowly added to it at the same temperature. The reaction mixture was stirred for about 36 hours from 20° C to 25° C. After completion of the reaction, 4-bromo-1-chloro-2-(4-ethoxybenzyl)benzene was obtained by further purification.
4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 561)Lieferanten
461432-23-5()Verwandte Suche:
- 5-bromo-2-chloro-4’-ethoxydiphenylmethane
- 4-(5-Bromo-2-chlorobenzyl)phenyl ethyl ether
- Dapagliflozin Intermediate 1
- 4-broMo-1-chloro-2-[(4-ethoxyphenyl)Methyl]-
- 2-(4-Methoxybenzyl)-4-broMo-1-chlorobenzene
- 1-(5-broMo-2-chlorobenzyl)-4-ethoxybenzene
- 5-broMo-2-chloro-4&rsquo
- Dapagliflozin Intermediate II
- Dapagliflozin Intermediate 2
- 5-bromo-2-chloro-4'-ethoxydiphenylmethane###461432-23-5
- (5-bromo-2-chlorobenzyl)-4-ethoxybenzene
- 4-(5-Brom-2-chlorbenzyl)phenyl-ethylether
- Dapagliflozin Impurity 15
- Dapagliflozin-13
- 4-(Dibenzofuranyl)boronic
- 4-(5-Bromo-2-chlorobenzy)phenylethyl ester
- Dapagliflozin Impurity 82
- 4-Bromo-1-chloro-2-(4-ethoxybenzyl)
- Dapagliflozin Despyranose Bromo Impurity
- 4-Brom-1-chlor-2-(4-ethoxybenzyl)benzol
- 5-bromo-2-chloro-4’-ethoxydiphenylmethane ISO 9001：2015 REACH
- 4-(3-((1-ethoxyethoxy)methyl)-4-bromophenoxy)benzonitrile
- Supply 5-bromo-2-chloro-4'-ethoxydiphenylmethane
- Dapaglifozin DAP Bromo
- 5-bromo-2-chloro-4-ethoxydiphenylmethaneQ: What is
5-bromo-2-chloro-4-ethoxydiphenylmethane Q: What is the CAS Number of
5-bromo-2-chloro-4-ethoxydiphenylmethane Q: What is the storage condition of
5-bromo-2-chloro-4-ethoxydiphenylmethane Q: What are the applications of
5-bromo-2-chloro-4-ethoxydiphenylmethane
- Benzene, 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]-
- Dapagliflozin Bromo impurity
- 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene
- Dapagliflozin Intermediate/ 5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane
- 4-(5- bromo -2- chlorobenzyl) phenethyl ether
- 5-Bromo-2-chIoro-4’-ethoxydiphenyImethane
- 4-Bromo-1-ChIoro 2-4-EthoxybenzyI-Benzene
- 4-bromo-l-chloro-2-(4-ethoxybenzyl)benzene
- 2-(4-ethoxybenzyl)-4-bromo-1-chloro benzene
- 5-bromo-2-chloro-4’-ethoxydiphenylmethane, Or 4-(5-Bromo-2-chlorobenzyl)phenyl ethyl ether
- (5-Bromo-2-chlorobenzyl)phenyl ethyl ether
- 5-bromo-2-chloro-4'-ethoxydiphenylmethane
- 6-bromo-2-chloro-4’-ethoxydiphenylmethane
- 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene
- 5-bromo-2-chloro-4’-ethoxydiphenylmethan
- 461432-23-5
- 61432-23-5
- 100134-06-9
- 9461432-23-5
- C15H14BrClO
- Halides
- Phenyls & Phenyl-Het
- 461432-23-5
- ADVANCED INT.
