ANTI-ABCB4 (HUMAN) Chemische Eigenschaften,Einsatz,Produktion Methoden
Allgemeine Beschreibung
Multidrug resistance protein 3 (MDR3) is also known as ATP binding cassette subfamily B member 4. It is expressed in hepatocytes and made up of 1279 amino acids. The gene encoding it is localized on human chromosome 7q21.12 and consists of 27 exons.
Biochem/physiol Actions
Multidrug resistance protein 3 (MDR3) acts as an ATP-dependent exporter and transfers phospholipids, particularly phosphatidylcholine (PC), into bile. Dysfunctioning of MDR3 leads to excess of bile salts in primary bile and further leads to liver diseases.
ANTI-ABCB4 (HUMAN) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte