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BI-2865

BI-2865 Struktur
2937327-93-8
CAS-Nr.
2937327-93-8
Englisch Name:
BI-2865
Synonyma:
BI-2865;BI-2865, 10 mM in DMSO
CBNumber:
CB713546660
Summenformel:
C23H27N7O2S
Molgewicht:
465.57
MOL-Datei:
2937327-93-8.mol

BI-2865 Eigenschaften

Siedepunkt:
708.7±70.0 °C(Predicted)
Dichte
1.38±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
pka
9.35±0.40(Predicted)
Aggregatzustand
Solid
Farbe
Light yellow to brown

Sicherheit

BI-2865 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

BI-2865 is a none-covalent pan-KRAS Inhibitor. BI-2865 blocked nucleotide exchange to prevent the activation of wild-type KRAS and a broad range of KRAS mutants, including G12A/C/D/F/V/S, G13C/D, V14I, L19F, Q22K, D33E, Q61H, K117N and A146V/T. Inhibition of downstream signaling and proliferation was restricted to cancer cells harboring mutant KRAS, and drug treatment suppressed KRAS mutant tumor growth in mice without having a detrimental effect on animal weight.

BI-2865 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


BI-2865 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 31)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hubei Chuchang Biotech Co., Ltd.
+undefined15623860702
info@chuchangbiotech.com China 202 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Hubei Chuchang Chemical Co., Ltd 18; 15623560702
Joy.Ren@aliyun.com China 160 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581
sales@chemhifuture.com China 5127 58
Changzhou Borl Biotechnology Co.,LTD 13606124132;13656121842
luyan0021@163.com China 218 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185
sales-cpd@caerulumpharma.com China 3466 58
Shanghai Pansopharm Technology Co., Ltd. 021-20962833 15316628753
sales@pansopharm.com China 611 60
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266
China 4589 55
ShangHai Angti Biotechnology Co., Ltd. 13764913901
info@angtibio.com China 5023 55
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994
2853530910@QQ.com China 8011 62

  • BI-2865
  • BI-2865, 10 mM in DMSO
  • 2937327-93-8
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