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bis(3',5')-cyclic diguanylic acid

bis(3',5')-cyclic diguanylic acid Struktur
61093-23-0
CAS-Nr.
61093-23-0
Englisch Name:
bis(3',5')-cyclic diguanylic acid
Synonyma:
c-di-GMP;5GP-5GP;Cyclic di-GMP;cyclic diguanylate;Cyclic-di-GMP Ammonium;Cyclic-di-GMP(c-di-GMP);CyclicdiGMP,Cyclic di GMP;3',5'-Cyclic diguanylic acid;Cyclic-di-GMP，cyclic diguanylate;bis(3',5')-cyclic diguanylic acid
CBNumber:
CB71335661
Summenformel:
C20H24N10O14P2
Molgewicht:
690.41
MOL-Datei:
61093-23-0.mol

bis(3',5')-cyclic diguanylic acid Eigenschaften

Schmelzpunkt:
193-196 °C (decomp)
Dichte
2.70±0.1 g/cm3(Predicted)
storage temp. 
-20°C
Aggregatzustand
powder
pka
0.66±0.70(Predicted)
Farbe
white to beige
Wasserl?slichkeit
Soluble in Water

Sicherheit

bis(3',5')-cyclic diguanylic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Cyclic-di-GMP sodium salt has been used as a quorum sensing molecule.

Definition

ChEBI: A cyclic purine dinucleotide that is the 3',5'-cyclic dimer of MP.

Biochem/physiol Actions

Cyclic-di-GMP is a naturally occurring small molecule that acts as a bacterial second messenger to regulate important signaling mechanisms in prokaryotes that control bacterial survival, adhesion, colonization, biofilm formation, and virulence factors production. During infections Cyclic-di-GMP is bound by host STING (stimulator of interferon genes) leading to expression of interferon genes, activating innate immune responses. c-di-GMP has been found in eukarotic systems acting not only in immune response, but as an inhibitor of the pacemaker I(f) current in the heart.

bis(3',5')-cyclic diguanylic acid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu

Downstream Produkte

bis(3',5')-cyclic diguanylic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 81)Lieferanten
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NewCan Biotech Limited 		+86-0571-86912261 +8613735419629
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TargetMol Chemicals Inc.
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 Mandy@hangyubiotech.com China 10986 58
R&D Scientific Inc. 		+1-2266000236
sales@rdscientific.com Canada 1570 58
  • bis(3',5')-cyclic diguanylic acid
  • Cyclic diguanosine monophosphate ( c-diGMP/c-di-GMP ) / cyclic bis ( 3' > 5' ) diguanylic acid
  • Cyclic di-GMP
  • 5GP-5GP
  • Cyclic-di-GMP，cyclic diguanylate
  • cyclic diguanylate
  • 3'-Guanylic acid, guanylyl-(3'→5')-, cyclic nucleotide
  • Cyclic-di-GMP(c-di-GMP)
  • Cyclic-di-GMP Ammonium
  • c-di-GMP
  • CyclicdiGMP,Cyclic di GMP
  • Bis-(3',5')-cyclic-di-guanosine monophosphate, sodium salt
  • Cyclic diguanosine monophosphate(c-digmp/c-di-gmp)/ cyclic bis diguanylic acid
  • 3',5'-Cyclic diguanylic acid
  • bis(3',5')-cyclic diguanylic acid
  • (1S,6R,8R,9R,10S,15R,17R,18R)-8,17-bis(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,9,12,18-tetrahydroxy-2,4,7,11,13,16-hexaoxa-3λ?,12λ?-diphosphatricyclo[13.3.0.0?,1?]octadecane-3,12-dione
  • 61093-23-0
  • C20H24N10O14P2
  • Nucleotide
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