9-Chlor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-propionat
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- CAS-Nr.
- 5534-18-9
- Bezeichnung:
- 9-Chlor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-propionat
- Englisch Name:
- Beclomethasone 17-propionate
- Synonyma:
- 17-BMP;Beclomethasone Impurity 2;BECLOMETHASONE 17-PROPIONATE;Beclomethasone EP Impurity H;BECLOMETHASONE 17-MONO PROPIOTE;beclomethasone 17-monopropionate;9-Chloro-11beta,21-dihydroxy-16beta;Beclomethasone Propionate Impurity H;Beclometasone Dipropionate Impurity H;Beclomethasone Dipropionate Impurity H
- CBNumber:
- CB6907138
- Summenformel:
- C25H33ClO6
- Molgewicht:
- 464.97892
- MOL-Datei:
- 5534-18-9.mol
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9-Chlor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-propionat Eigenschaften
- Schmelzpunkt:
- 124-126?C
- Siedepunkt:
- 608.9±55.0 °C(Predicted)
- Dichte
- 1.30±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- L?slichkeit
- DMSO: 100 mg/mL (215.06 mM)
- Aggregatzustand
- Solid
- pka
- 12.98±0.10(Predicted)
- Farbe
- White to Light Yellow
- InChIKey
- OHYGPBKGZGRQKT-MVAAQJHONA-N
- SMILES
- C1(=O)C=C2[C@](C)(C=C1)C1(Cl)[C@]([H])([C@@]3([H])[C@@](C[C@@H]1O)(C)[C@@](OC(=O)CC)(C(=O)CO)[C@@H](C)C3)CC2 |&1:4,10,12,14,16,19,29,r|
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
 
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H341 |
Kann vermutlich genetische Defekte verursachen. |
Keimzellmutagenit?t |
Kategorie 2 |
Warnung |
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P201,P202, P281, P308+P313, P405,P501 |
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| Sicherheit |
| P201 |
Vor Gebrauch besondere Anweisungen einholen. |
| P202 |
Vor Gebrauch alle Sicherheitshinweise lesen und verstehen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P281 |
Vorgeschriebene pers?nliche Schutzausrüstung verwenden. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P308+P313 |
BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P330 |
Mund ausspülen. |
| P405 |
Unter Verschluss aufbewahren. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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9-Chlor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-propionat Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Beclomethasone 17-propionate is a glucocorticoid receptor agonist and an active metabolite of the glucocorticoid prodrug beclomethasone dipropionate. It can effectively inhibit cytokine production in lung macrophages of chronic obstructive pulmonary disease (COPD) and can be used in the study of diseases related to respiratory inflammation.
Chemische Eigenschaften
Light Yellow Solid
Verwenden
Active metabolite of Beclomethasone Dipropionate (BDP).
9-Chlor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-propionat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
9-Chlor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-propionat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 76)Lieferanten
5534-18-9(9-Chlor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17-propionat)Verwandte Suche:
- 9-chloro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate
- beclomethasone 17-monopropionate
- 9-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 17-propanoate
- 9-Chloro-11,21-dihydroxy-16-methyl-17-propionyloxypregna-1,4-diene-3,20-dione
- 9-Chloro-11β,21-dihydroxy-16β-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
- 9-Chloro-11β-hydroxy-16β-methyl-17α-(propionyloxy)-21-hydroxypregna-1,4-diene-3,20-dione
- 9-Chloro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-propionate
- Beclomethasone EP Impurity H
- (11,16)-9-Chloro-11,21-dihydroxy-16-methyl-17-(1-oxopropoxy)-pregna-1,4-diene-3,20-dione
- Beclomethasone-17-monopropionate reference substance
- Beclomethasone Dipropionate EP Impurity H
- Beclomethasone Propionate Impurity H(EP)
- Beclomethasone Dipropionate impurity 5/Beclomethasone Dipropionate EP Impurity H/Beclomethasone-17-monopropionate
- Beclomethasone Dipropionate Impurity H
- Beclometasone Dipropionate EP Impurity H
- Beclomethasone Dipropionate EP Impurity H (Beclomethasone-17-monopropionate)
- 9-Chloro-11beta,21-dihydroxy-16beta
- 17-BMP
- Pregna-1,4-diene-3,20-dione, 9-chloro-11,21-dihydroxy-16-methyl-17-(1-oxopropoxy)-, (11β,16β)-
- Beclomethasone Impurity 2
- Beclomethasone propionate EP impurity H
- Beclomethasone Impurity 7(Beclometasone Dipropionate EP Impurity H)
- Beclomethasone Propionate Impurity H
- Beclomethasone-17-Propionate D5Q: What is
Beclomethasone-17-Propionate D5 Q: What is the CAS Number of
Beclomethasone-17-Propionate D5 Q: What is the storage condition of
Beclomethasone-17-Propionate D5 Q: What are the applications of
Beclomethasone-17-Propionate D5
- Beclomethasone-17-PropionateQ: What is
Beclomethasone-17-Propionate Q: What is the CAS Number of
Beclomethasone-17-Propionate Q: What is the storage condition of
Beclomethasone-17-Propionate Q: What are the applications of
Beclomethasone-17-Propionate
- Beclometasone Dipropionate Related Compound H
- Beclometasone Dipropionate USP Related Compound H
- BECLOMETHASONE 17-MONO PROPIOTE
- Beclometasone Dipropionate Impurity H
- Beclometasone Propionate EP Impurity H
- 1, 4-PREGNADIEN-9α-CHLORO-16β-METHYL-11β, 17, 21-TRIOL-3, 20-DIONE 17-PROPIONATE
- (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
- Beclometasone (Beclomethasone) Dipropionate EP Impurity H (Beclomethasone Dipropionate USP Related Compound H, Beclomethasone-17-Monopropionate)
- 9-Chloro-11beta,21-dihydroxy-16beta-methyl-3,20-dioxopregna-1,4-dien-17-yl Propanoate (Beclometasone
- BECLOMETHASONE 17-PROPIONATE
- 5534-18-9
- Metabolites & Impurities
- Steroids
