1H-pyrrolo[2,3-b]pyridine-6-carbonitrile
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- CAS-Nr.
- 189882-33-5
- Englisch Name:
- 1H-pyrrolo[2,3-b]pyridine-6-carbonitrile
- Synonyma:
- 6-CYANO-7-AZAINDOLE;7-Azaindole-6-carbonitrile;6-Cyano-1H-pyrrolo[2,3-b]pyridine;PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE;1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE;1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile(9CI);1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE ISO 9001：2015 REACH
- CBNumber:
- CB6748962
- Summenformel:
- C8H5N3
- Molgewicht:
- 143.15
- MOL-Datei:
- 189882-33-5.mol
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1H-pyrrolo[2,3-b]pyridine-6-carbonitrile Eigenschaften
- Schmelzpunkt:
- 187.4 °C
- Siedepunkt:
- 463.9±28.0 °C(Predicted)
- Dichte
- 1.29±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 6.56±0.40(Predicted)
1H-pyrrolo[2,3-b]pyridine-6-carbonitrile Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
7-Azaindole, as a bioisostere of indole or purine, is widely used in drug development. Among them, 1H-pyrrolo[2,3-b]pyridine-6-carbonitrile is a key intermediate for the synthesis of a class of selective cyclin-dependent kinase (CDK) 7 inhibitors. Among mammalian CDKs, CDK7 has a unique integrated kinase activity that helps regulate the cell cycle and gene transcription. 1H-pyrrolo[2,3-b]pyridine-6-carbonitrile can be prepared using 7-azaindole-7-oxide as a raw material.
Chemische Eigenschaften
Class white powder
1H-pyrrolo[2,3-b]pyridine-6-carbonitrile Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1H-pyrrolo[2,3-b]pyridine-6-carbonitrile Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 116)Lieferanten
- 1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE
- 6-Cyano-1H-pyrrolo[2,3-b]pyridine
- 1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile(9CI)
- PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE
- 7-Azaindole-6-carbonitrile
- 1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE ISO 9001：2015 REACH
- 6-CYANO-7-AZAINDOLE
- 189882-33-5
- Azaindoles
- PYRIDINE
