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3-Hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl-3-formyl-2,4-dihydroxy-6-methylbenzoat

ATRANORIN Struktur
479-20-9
CAS-Nr.
479-20-9
Bezeichnung:
3-Hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl-3-formyl-2,4-dihydroxy-6-methylbenzoat
Englisch Name:
ATRANORIN
Synonyma:
Atrarin;USNARIN;PARMELIN;ATRANORIN;NSC-685591;ATRANORIN(P);Usnarin acid;Atranorin-RM;Parmelin acid;Atranoric acid
CBNumber:
CB6665973
Summenformel:
C19H18O8
Molgewicht:
374.34
MOL-Datei:
479-20-9.mol

3-Hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl-3-formyl-2,4-dihydroxy-6-methylbenzoat Eigenschaften

Schmelzpunkt:
156-158°C
storage temp. 
Store at -20°C
L?slichkeit
Chloroform: soluble,DMSO: soluble
Aggregatzustand
A crystalline solid
Farbe
White to off-white
LogP
6.140 (est)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Toxizit?t skn-gpg 5% CODEDG 11,168,1984
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H317 Kann allergische Hautreaktionen verursachen. Sensibilisierung der Haut Kategorie 1A Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Sicherheit
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P302+P352 BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.

3-Hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl-3-formyl-2,4-dihydroxy-6-methylbenzoat Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Atranorin is a depside lichen metabolite that has been found in S. alpinum and has diverse biological activities. It is active against the bacteria B. cereus, B. subtilis, S. aureus, S. faecalis, P. vulgaris, L. monocytogenes, and A. hydrophila (MICs = 1.67, 0.38, 26.7, 13.4, 3.34, 9.83, and 1.67 mM, respectively), the fungi C. albicans and C. glabrata (MIC = 26.7 mM for both), as well as the mycobacterium M. aurum (MIC = 250 μg/ml). Atranorin is cytotoxic to A270, HL-60, and Jurkat cancer cells (IC50s = 197.9, 93.5, and 181.6 μM, respectively) but not HeLa, MCF-7, SK-BR-3, or HT-29 cancer cells (IC50s = >200 μM). It inhibits acetic acid-induced writhing in mice when administered orally at doses of 200 and 400 mg/kg. Atranorin (200 and 400 mg/kg, p.o.) also reduces paw licking and biting in the second, but not first, phase of the formalin test when administered 30 minutes prior to formalin in mice.

Verwenden

Component in extracts of oak moss used as fragrance. Atranorin is a derivative compound of Chloratranorin (C364120), which are metabolites of Evernia prunastri and functions as antioxidant, antimicrobial and potential anticancer agents.

Hazard

A poison by skin contact. A skin irritant.

Sicherheitsprofil

A poison by skin contact. A skin irritant. When heated to decomposition it emits acrid smoke and irritating vapors.

3-Hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl-3-formyl-2,4-dihydroxy-6-methylbenzoat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


3-Hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl-3-formyl-2,4-dihydroxy-6-methylbenzoat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 92)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897
sales@biopurify.com China 3772 58
Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22963 58
TopScience Biochemical
00852-68527855
info@itopbiochem.com China Hong Kong 902 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29810 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Aktin Chemicals, Inc.
028-85159085
info@aktinchem.com CHINA 1025 58
Labnetwork lnc.
+86-27-50766799 +8618062016861
contact@labnetwork.com China 19987 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38631 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43340 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501
product@acmec-e.com China 33338 58

479-20-9(3-Hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl-3-formyl-2,4-dihydroxy-6-methylbenzoat)Verwandte Suche:


  • PARMELIN
  • USNARIN
  • ATRANORIN
  • 3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl 3-formyl-2,4-dihydroxy-6-methylbenzoate
  • 3-Formyl-2,4-dihydroxy-6-methylbenzoic acid 3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl ester
  • NSC-685591
  • ATRANORIN(P)
  • Atrarin
  • Benzoic acid,3-formyl-2,4-dihydroxy-6-methyl-,3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl ester
  • 4-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-3,12,14-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-oxolanone
  • 3-Hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl-3-formyl-2,4-dihydroxy-6-methylbenzoat
  • Atranoric acid
  • Parmelin acid
  • Usnarin acid
  • Atranorin(P)(Request Quote)
  • Atranorin-RM
  • 479-20-9
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