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N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine

N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine Struktur
1438071-12-5
CAS-Nr.
1438071-12-5
Englisch Name:
N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine
Synonyma:
GSK-2945;GSK-2945 (GSK2945 );GSK 2945 DISCONTINUED. Please see G797405;2-Thiophenemethanamine, N-[(4-chloro-2-methylphenyl)methyl]-N-[(4-chlorophenyl)methyl]-5-nitro-;N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine
CBNumber:
CB63464337
Summenformel:
C20H18Cl2N2O2S
Molgewicht:
421.34
MOL-Datei:
1438071-12-5.mol

N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine Eigenschaften

Siedepunkt:
525.0±45.0 °C(Predicted)
Dichte
1.363±0.06 g/cm3(Predicted)
L?slichkeit
Acetonitrile (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Sonicated)
pka
5.23±0.50(Predicted)
Aggregatzustand
Solid
Farbe
Off-White to Light Beige
Stabilit?t:
Hygroscopic

Sicherheit

N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

GSK 2945 is an antagonist with high specificity for REV-ERBα, Nuclear heme receptor reverse erythroblastosis virus, which is known to regulate circadian rhythm and more specifically, regulation of cholesterol 7α-hydroxylase (CYP7A1) and bile acid synthesis.

N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

4-CHLORO-2-METHYLBENZALDEHYDE 4-Chlorbenzylamin

Downstream Produkte

N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • N-[(4-chloro-2-methylphenyl)methyl]-1-(4-chlorophenyl)-N-[(5-nitrothiophen-2-yl)methyl]methanamine
  • GSK-2945
  • GSK-2945 (GSK2945 )
  • 2-Thiophenemethanamine, N-[(4-chloro-2-methylphenyl)methyl]-N-[(4-chlorophenyl)methyl]-5-nitro-
  • GSK 2945 DISCONTINUED. Please see G797405
  • 1438071-12-5
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