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SMI-16a

SMI-16a Struktur
587852-28-6
CAS-Nr.
587852-28-6
Englisch Name:
SMI-16a
Synonyma:
SMI-16a;SMI-16A;SMI 16A;SMI16A;PIM1/2 Kinase Inhibitor VI;SMI-16a(PIM1/2 Kinase Inhibitor VI);5-(4-propoxybenzylidene)thiazolidine-2,4-dione;2,4-Thiazolidinedione, 5-[(4-propoxyphenyl)methylene]-;SMI-16a,SMI 16a,inhibit,SMI16a,Pim,Inhibitor,Pim kinases
CBNumber:
CB63313558
Summenformel:
C13H13NO3S
Molgewicht:
263.31
MOL-Datei:
587852-28-6.mol

SMI-16a Eigenschaften

Schmelzpunkt:
186.3-188.4 °C
Dichte
1.303±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
L?slichkeit
Ethanol:3.0(Max Conc. mg/mL);11.39(Max Conc. mM)
Aggregatzustand
A solid
pka
7.27±0.20(Predicted)
Farbe
Light yellow to yellow

Sicherheit

SMI-16a Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

SMI-16a is a Pim-1 kinase inhibitor (IC50 = 63 nM). It is selective for Pim-1 over a panel of 60 kinases. SMI-16a (5 μM) inhibits phosphorylation of the Pim-1 target protein Bad in DU145-Pim cells and inhibits the growth of PC3, DU145, LNCaP, K562, and MV4-11 cancer cells. It induces apoptosis and cell cycle arrest at the G1 phase in DU145 cells.

SMI-16a Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

SMI-16a Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 55)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32951 60
career henan chemical co 		+86-0371-86658258 +8613203830695
 factory@coreychem.com China 29811 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289
 contact@trustwe.com China 5738 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38470 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66099280 17798518460
 cfzhang@aikonchem.com China 19915 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9806 58
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903
 3008007409@qq.com China 27313 60
  • SMI-16a
  • PIM1/2 Kinase Inhibitor VI
  • SMI-16a(PIM1/2 Kinase Inhibitor VI)
  • SMI-16A;SMI 16A;SMI16A
  • 2,4-Thiazolidinedione, 5-[(4-propoxyphenyl)methylene]-
  • SMI-16a,SMI 16a,inhibit,SMI16a,Pim,Inhibitor,Pim kinases
  • 5-(4-propoxybenzylidene)thiazolidine-2,4-dione
  • 587852-28-6
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