(R)-1-benzyl-5-methyl-1,4-diazepane
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- CAS-Nr.
- 1620097-06-4
- Englisch Name:
- (R)-1-benzyl-5-methyl-1,4-diazepane
- Synonyma:
- (R)-1-benzyl-5-methyl-1,4-diazepane;(5R)-1-benzyl-5-methyl-1,4-diazepane;Relebactam Impurity 4;Suvorexant Impurity 27;Suvorexant (MK-4305) intermediate;(R)-1-benzyl-5-methyl-1,4-diazepane(For export only);(5S)-Hexahydro-5-methyl-1-(phenylmethyl)-1H-1,4-diazepine;(5R)-Hexahydro-5-methyl-1-(phenylmethyl)-1H-1,4-diazepine;1H-1,4-Diazepine, hexahydro-5-methyl-1-(phenylmethyl)-, (5R)-;Suvorexant intermediate (5R)-Hexahydro-5-methyl-1-(phenylmethyl)-1H-1,4-diazepine
- CBNumber:
- CB63040519
- Summenformel:
- C13H20N2
- Molgewicht:
- 204.31
- MOL-Datei:
- 1620097-06-4.mol
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(R)-1-benzyl-5-methyl-1,4-diazepane Eigenschaften
- Siedepunkt:
- 296.1±28.0 °C(Predicted)
- Dichte
- 0.974±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 10.65±0.40(Predicted)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
(R)-1-benzyl-5-methyl-1,4-diazepane Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
(5R)-1-Benzyl-5-methyl-1,4-diazepane is a synthetic substance with inhibitory activity on calcium channels. It has been shown to be useful for the treatment of epilepsy and other neurological disorders in animal models.
synthetische
(R)-4-benzyl-7-methyl-1,4-diazepan-2,5-dione(6 mmol)Was dissolved in 60 ml of dry THF, and 1.35 g of LiAlH4 (36 mmol) was added portionwise under ice-cooling, and stirred at 25℃ for 4 h.After cooling to -10 ℃, 1.5 ml of H20 was added and 1.5 ml of 15% NaOH, 4.5 ml of H20 and a portion of MgS04 were added, stirred for 1 h, suction filtered and dried to afford 1.2 g of an oil yield 97.56%。
(R)-1-benzyl-5-methyl-1,4-diazepane Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(R)-1-benzyl-5-methyl-1,4-diazepane Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 60)Lieferanten
- (5R)-Hexahydro-5-methyl-1-(phenylmethyl)-1H-1,4-diazepine
- Suvorexant intermediate (5R)-Hexahydro-5-methyl-1-(phenylmethyl)-1H-1,4-diazepine
- Suvorexant (MK-4305) intermediate
- 1H-1,4-Diazepine, hexahydro-5-methyl-1-(phenylmethyl)-, (5R)-
- (R)-1-benzyl-5-methyl-1,4-diazepane(For export only)
- (R)-1-benzyl-5-methyl-1,4-diazepane
- (5R)-1-benzyl-5-methyl-1,4-diazepane
- (5S)-Hexahydro-5-methyl-1-(phenylmethyl)-1H-1,4-diazepine
- Relebactam Impurity 4
- Suvorexant Impurity 27
- 1620097-06-4