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1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole

1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Struktur
135270-07-4
CAS-Nr.
135270-07-4
Englisch Name:
1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole
Synonyma:
Efluconazole impurity 7;Efinaconazole Impurity 18;Efinaconazole Related Impurity 4;(1H-1,2,4-triazol-1-yl)methyl>(2S,3R)-2-(2,4-difluorophenyl)-3-methyl-2-<(2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol...;(2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane;1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole;1H-1,2,4-Triazole, 1-[[(2S,3R)-2-(2,4-difluorophenyl)-3-methyloxiranyl]methyl]- (9CI);1-(((2S,3R)-2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole (Efinaconazole Impurity)
CBNumber:
CB62705242
Summenformel:
C12H11F2N3O
Molgewicht:
251.23
MOL-Datei:
135270-07-4.mol

1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Eigenschaften

Siedepunkt:
371.6±52.0 °C(Predicted)
Dichte
1.41±0.1 g/cm3(Predicted)
pka
2.75±0.10(Predicted)

Sicherheit

1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

(2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane is a useful synthetic intermediate in the synthesis of ent-Efinaconazole (E435075); the S,S-enantiomer of Efinaconazole (E435070) which is a topical antifungal for onychomycosis.

1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • 1-(((2S,3R)-2-(2,4-difluorophenyl)-3-Methyloxiran-2-yl)Methyl)-1H-1,2,4-triazole
  • Efinaconazole Related Impurity 4
  • (2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane
  • (1H-1,2,4-triazol-1-yl)methyl>
  • (2S,3R)-2-(2,4-difluorophenyl)-3-methyl-2-<
  • Efinaconazole Impurity 18
  • 1H-1,2,4-Triazole, 1-[[(2S,3R)-2-(2,4-difluorophenyl)-3-methyloxiranyl]methyl]- (9CI)
  • (2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol...
  • 1-(((2S,3R)-2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole (Efinaconazole Impurity)
  • Efluconazole impurity 7
  • 135270-07-4
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