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PI3K inhibitor

PI3K inhibitor Struktur
1202884-94-3
CAS-Nr.
1202884-94-3
Englisch Name:
PI3K inhibitor
Synonyma:
CAY10626;PI3K-IN-22;Antitumor Drug;PI3K inhibitor;CAY10626, PI3Kalpha/mTOR inhibitor;N-[2-(dimethylamino)ethyl]-N-methyl-4-[({4-[4-morpholin-4-yl-7-(2,2,2-trifluoroethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]phenyl}carbamoyl)amino]benzamide;BenzaMide, N-[2-(diMethylaMino)ethyl]-N-Methyl-4-[[[[4-[4-(4-Morpholinyl)-7-(2,2,2-trifluoroethyl)-7H-pyrrolo[2,3-d]pyriMidin-2-yl]phenyl]aMino]carbonyl]aMino]-
CBNumber:
CB62487667
Summenformel:
C31H35F3N8O3
Molgewicht:
624.66
MOL-Datei:
1202884-94-3.mol

PI3K inhibitor Eigenschaften

Dichte
1.35±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMF: 15 mg/ml; DMSO: 15 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml
Aggregatzustand
A crystalline solid
pka
13.74±0.70(Predicted)

Sicherheit

PI3K inhibitor Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

The PI3Kinases are important downstream effectors of KRAS signaling. In preclinical studies, buparlisib (BKM120), a PI3K inhibitor, when combined with MEK inhibitor (PD1056309) led to significant synergistic activity in KRAS mutant NSCLC cell lines.

PI3K inhibitor Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

PI3K inhibitor Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 28)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
LETOPHARM LIMITED +86-21-5821 5861
sales@letopharm.com China 2384 58
BOC Sciences 16314854226
 info@bocsci.com United States 9923 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11218 58
Shanghai Zeye Biotechnology Co., Ltd. 021-61998551 13122364865
 sale1@shzysw.net China 9772 58
Energy Chemical 021-58432009 400-005-6266
 marketing@energy-chemical.com China 44918 58
TargetMol Chemicals Inc. 4008200310
 marketing@tsbiochem.com China 24644 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
 customer_service@efebio.com China 11974 58
  • PI3K inhibitor
  • Antitumor Drug
  • CAY10626
  • BenzaMide, N-[2-(diMethylaMino)ethyl]-N-Methyl-4-[[[[4-[4-(4-Morpholinyl)-7-(2,2,2-trifluoroethyl)-7H-pyrrolo[2,3-d]pyriMidin-2-yl]phenyl]aMino]carbonyl]aMino]-
  • N-[2-(dimethylamino)ethyl]-N-methyl-4-[({4-[4-morpholin-4-yl-7-(2,2,2-trifluoroethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]phenyl}carbamoyl)amino]benzamide
  • PI3K-IN-22
  • CAY10626, PI3Kalpha/mTOR inhibitor
  • 1202884-94-3
  • C31H35F3N8O3
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