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3-(5H-Dibenzo[a,d]cyclohepten-5-yliden)propyl(dimethyl)ammoniumchlorid

Cyclobenzaprine hydrochloride Struktur
6202-23-9
CAS-Nr.
6202-23-9
Bezeichnung:
3-(5H-Dibenzo[a,d]cyclohepten-5-yliden)propyl(dimethyl)ammoniumchlorid
Englisch Name:
Cyclobenzaprine hydrochloride
Synonyma:
CYCLOBENZAPRINE HCL;flexeril;Flexiba;Lisseril;flexiban;Cyclobezaprine HCl;MK130 hydrochloride;Nortriptyline EP Impurity E;Amitriptyline EP Impurity B;Cyclobenzaprine HCl (MK130)
CBNumber:
CB6238272
Summenformel:
C20H22ClN
Molgewicht:
311.85
MOL-Datei:
6202-23-9.mol

3-(5H-Dibenzo[a,d]cyclohepten-5-yliden)propyl(dimethyl)ammoniumchlorid Eigenschaften

Schmelzpunkt:
216-2180C
Flammpunkt:
9℃
storage temp. 
Inert atmosphere,Room Temperature
Wasserl?slichkeit
Completely soluble in water
L?slichkeit
≥15.59 mg/mL in DMSO; ≥5.32 mg/mL in EtOH; ≥54.3 mg/mL in H2O
Aggregatzustand
Solid
Farbe
White to Almost white
maximale Wellenl?nge (λmax)
290nm(lit.)
Merck 
14,2713
InChIKey
VXEAYBOGHINOKW-UHFFFAOYSA-N
CAS Datenbank
6202-23-9(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn,T,F
R-S?tze: 20/21/22-39/23/24/25-23/24/25-11
S-S?tze: 36-45-36/37-16-7
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS-Nr. HP0875000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29214990
Toxizit?t LD50 in mice (mg/kg): 35 i.v., 250 orally (Metysova)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H301 Giftig bei Verschlucken. Akute Toxizit?t oral Kategorie 3 Achtung GHS hazard pictogramssrc="/GHS06.jpg" width="20" height="20" /> P264, P270, P301+P310, P321, P330,P405, P501
Sicherheit
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

3-(5H-Dibenzo[a,d]cyclohepten-5-yliden)propyl(dimethyl)ammoniumchlorid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.

S-S?tze Betriebsanweisung:

S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Beschreibung

Cyclobenzaprine is a skeletal muscle relaxant that also has sedative properties. It has been shown to antagonize muscarinic receptors (Kis = 25, 60, and 6 nM for M1, M2, and M3, respectively), serotonin 5-HT2 receptors (Kis = 56 and 330 nM for 5-HT2C and 5-HT2B, respectively), and histamine H1 receptor (IC50 = 20 nM).

Chemische Eigenschaften

Crystalline Solid

Verwenden

Cyclobenzaprine hydrochloride cam be used as muscle relaxant (skeletal).

Definition

ChEBI: The hydrochloride salt of cyclobenzaprine. A centrally acting skeletal muscle relaxant, it is used in the symptomatic treatment of painful muscle spasm.

Allgemeine Beschreibung

Cyclobenzaprine is a tricyclic agent, which has anti-depressant and anti-cholinergic properties. It lowers the tonic somatic motor activity of motor neuron systems. Cyclobenzaprine prevents the uptake of?noradrenaline. It is used to treat neck,?back and myofascial pain. Cyclobenzaprine functions as a nerve impulse inhibitor.

3-(5H-Dibenzo[a,d]cyclohepten-5-yliden)propyl(dimethyl)ammoniumchlorid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Hydrogenchlorid 3-Chlorpropyl(dimethyl)amin

Downstream Produkte

3-(5H-Dibenzo[a,d]cyclohepten-5-yliden)propyl(dimethyl)ammoniumchlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 329)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Guangzhou Tengyue Chemical Co., Ltd. 		+86-86-18148706580 +8618826483838
 evan@tyvovo.com China 148 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806
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Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512
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Nanjing Finetech Chemical Co., Ltd. 		025-85710122 17714198479
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ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
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career henan chemical co 		+86-0371-86658258 +8613203830695
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Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873
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CONIER CHEM AND PHARMA LIMITED 		+8618523575427
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Antai Fine Chemical Technology Co.,Limited 		18503026267
 info@antaichem.com CHINA 9636 58

6202-23-9(3-(5H-Dibenzo[a,d]cyclohepten-5-yliden)propyl(dimethyl)ammoniumchlorid)Verwandte Suche:

  • 3-(5h-dibenzo(a,d)cyclohepten-5-ylidene)-n,n-dimethyl-1-propanaminhydroc
  • 5-(3-dimethylaminopropylidene)-5h-dibenzo-(a,d)cycloheptenehydrochloride
  • CYCLOBENZAPRINEHYDROCHLORIDE,USP
  • Lisseril
  • Proheptatriene hydrochloride
  • Cyclobenzaprine hydrochloride,5-(3-Dimethylaminopropylidene)dibenzo[a,e]cycloheptatriene hydrochloride
  • Cyclobenzaprine Hydrochloride (200 mg)
  • 3-(5H-Dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine hydrochloride
  • 1-PropanaMine,3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-diMethyl-, hydrochloride (1:1)
  • 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine, hydrochloride (1:1)
  • Cyclobenzaprine hydrochloride solution
  • d)cycloheptene-delta(sup5)-gamma-propylamine,n,n-dimethyl-5h-dibenzo(hydr
  • flexiban
  • n,n-dimethyl-5h-dibenzo(a,d)cycloheptene-delta(sup5,gamma)-propylaminehydro
  • proheptatrienmonohydrochloride
  • CYCLOBENZAPRINE HYDROCHLORIDE
  • AMITRITYLINE HYDROCHLORIDE IMP B
  • 5-[3-DIMETHYLAMINOPROPYLIDENE]-DIBENZO[A,E]CYCLOHEPTATRIENE HYDROCHLORIDE
  • 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)propyl(dimethyl)ammonium chloride
  • 3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine Hydrochloride
  • Flexiba
  • 1-Propanamine, 3-(5H-dibenzoa,dcyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride
  • Nortriptyline EP Impurity E
  • Amitriptyline EP Impurity B HCl
  • Cyclobenzaprine hydrochloride, 98%, a peripherally-acting AAAD or DOPA decarboxylase inhibitor
  • Cyclobenzaprine Hydrochloride, Usp 99%
  • Amitriptyline hydrochloride impurity B
  • Cyclobenzaprine Hydrochloride(Flexeril,Yurelax)
  • Amitriptyline EP Impurity B
  • Cyclobenzaprine hydrochloride CRS
  • Cyclobenzaprine Hydrochloride >
  • Amitriptyline EP Impurity B HCl (Nortriptyline EP Impurity E HCl)
  • Cyclobezaprine HCl
  • Amitriptyline EP Impurity B (Cyclobenzaprine)
  • Cyclobenzaprine HCl (MK130)
  • Cyclobenzaprine HydrochlorideQ: What is Cyclobenzaprine Hydrochloride Q: What is the CAS Number of Cyclobenzaprine Hydrochloride Q: What is the storage condition of Cyclobenzaprine Hydrochloride Q: What are the applications of Cyclobenzaprine Hydrochloride
  • Cyclobenzaprine Hydrochloride (1154503)
  • Cyclobenzaprine (hydrochloride) (CRM)
  • Hydrochloride Cyclobenzaprine
  • MK130 hydrochloride
  • flexeril
  • CYCLOBENZAPRINE HCL
  • RSSYY(Perospirone Hydrochloride Hydrate)-1
  • Amitriptyline Hydrochloride EP Impurity B as Hydrochloride
  • Nortriptyline Hydrochloride EP Impurity E as Hydrochloride
  • Nortriptyline Hydrochloride Impurity E as Hydrochloride
  • Nortriptyline EP Impurity E HCl
  • Nortriptyline EP Impurity E HCl (Amitriptyline EP Impurity B HCl)
  • Cyclobenzaprine hydrochloride in methanol
  • Nortriptyline EP Impurity E (hydrochloride)
  • 6202-23-9
  • 6202-32-9
  • C20H21NClH
  • C20H22ClN
  • C20H21NHCl
  • Skeletal muscle relaxant; reduces muscle spasm by depression of brainstem neurons; 5-HT2 serotonin receptor antagonist.
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
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