ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate
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- CAS-Nr.
- 37178-37-3
- Englisch Name:
- ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate
- Synonyma:
- TV-1203;L-Dopa-Et;O-Ethyl-DOPA;L-DOPA Ethyl Ester;Levodopa ethyl ester;Levodopa Impurity 27;L-Dopa ethyl ester >=98% (HPLC);3-Hydroxy-L-tyrosine ethyl ester;L-Tyrosine, 3-hydroxy-, ethyl ester;3,4-Dihydroxy-L-phenylalanine ethyl ester
- CBNumber:
- CB61568662
- Summenformel:
- C11H15NO4
- Molgewicht:
- 225.24
- MOL-Datei:
- 37178-37-3.mol
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ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate Eigenschaften
- Siedepunkt:
- 394.2±37.0 °C(Predicted)
- Dichte
- 1.278±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: ≥12mg/mL at warmed to 60°C
- pka
- 9.67±0.20(Predicted)
- Aggregatzustand
- powder
- Farbe
- white to tan
ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Antiparkisonian.
Biochem/physiol Actions
L-Dopa ethyl ester is a prodrug of levodopa that has greater gastric solubility. The drug is rapidly hydrolyzed to levodopa by nonspecific esterases in the gastrointestinal tract. L-Dopa ethyl ester (etilevodopa)-carbidopa treatment was well tolerated but did not demonstrate better efficacy compared with standard levodopa-carbidopa treatment. L-Dopa ethyl ester should have a significant brain penetration following an administration by injection.
ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 25)Lieferanten
- O-Ethyl-DOPA
- TV-1203
- ethyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate
- L-DOPA Ethyl Ester
- 2(S)-Amino-3-(3,4-dihydroxyphenyl)propionic acid ethyl ester
- 3,4-Dihydroxy-L-phenylalanine ethyl ester
- 3-Hydroxy-L-tyrosine ethyl ester
- L-Dopa-Et
- Levodopa ethyl ester
- L-Tyrosine, 3-hydroxy-, ethyl ester
- L-Dopa ethyl ester >=98% (HPLC)
- Levodopa Impurity 27
- 37178-37-3