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Carebastine-d5

Carebastine-d5 Struktur
1189661-02-6
CAS-Nr.
1189661-02-6
Englisch Name:
Carebastine-d5
Synonyma:
Carebastine-d5;Valine Impurity 136;4-[4-[4-(DiphenylMethoxy-d5)-1-piperidinyl]-1-oxobutyl]-α,α-diMethylbenzeneacetic Acid;4-[4-[4-(Diphenylmethoxy-d5)-1-piperidinyl]-1-oxobutyl]-a,a-dimethylbenzeneacetic Acid;4-[4-[4-(Diphenylmethoxy-d5)-1-piperidinyl]-1-oxobutyl]-α,a-dimethylbenzeneacetic Acid
CBNumber:
CB61565757
Summenformel:
C32H37NO4
Molgewicht:
499.64048
MOL-Datei:
1189661-02-6.mol

Carebastine-d5 Eigenschaften

Schmelzpunkt:
72-74°C
storage temp. 
-20°C Freezer
L?slichkeit
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
Farbe
Off-White to Light Yellow

Sicherheit

Carebastine-d5 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Carebastine-d5 is intended for use as an internal standard for the quantification of carebastine by GC- or LC-MS. Carebastine is an active metabolite of ebastine and a histamine H1 receptor antagonist (Ki = 75.86 nM). It inhibits histamine-induced contraction of isolated guinea pig trachea (IC50 = 120 nM). It also inhibits histamine release from isolated rat peritoneal mast cells and human basophils when used at concentrations ranging from 30 to 100 μM. Carebastine decreases production of chemokine (C-C motif) ligand 5 (CCL5) and CCL2 in human nasal epithelial cells isolated from patients with nasal allergies.

Chemische Eigenschaften

Off-White Solid

Carebastine-d5 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Carebastine-d5 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 26)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32321 50
Cato Research Chemicals Inc. 020-81960175
min.he@cato-chem.com China 1955 55
Energy Chemical 021-58432009 400-005-6266
marketing1@energy-chemical.com China 44808 58
Foshan Treasure Biotechnology Co., Ltd 0757-85921206 18520245316
2329783215@qq.com China 12661 58
ChemeGen 中國 18818260767
sales@chemegen.com China 6973 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337
3427709316@qq.com China 7979 58
Shanghai isotope chemical co.,ltd 021-021-51600108 13062666369
sales@chinaisotope.com China 4271 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
customer_service@efebio.com China 11974 58
guoyungurui 18162595016; 18162595016
3287908757@qq.com China 10336 58
Nanjing Shizhou Biology Technology Co.,Ltd 17301488900
judy.xia@synzest.com China 12582 58

  • 4-[4-[4-(Diphenylmethoxy-d5)-1-piperidinyl]-1-oxobutyl]-α,a-dimethylbenzeneacetic Acid
  • Carebastine-d5
  • 4-[4-[4-(Diphenylmethoxy-d5)-1-piperidinyl]-1-oxobutyl]-a,a-dimethylbenzeneacetic Acid
  • 4-[4-[4-(DiphenylMethoxy-d5)-1-piperidinyl]-1-oxobutyl]-α,α-diMethylbenzeneacetic Acid
  • Valine Impurity 136
  • 1189661-02-6
  • C32H32D5NO4
  • Intermediates & Fine Chemicals
  • Isotope Labeled Compounds
  • Metabolites & Impurities
  • Pharmaceuticals
  • Isotope Labelled Compounds
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