2-(TRIMETHYLSILYL)ETHOXYMETHYLTRIPHENYLPHOSPHONIUM CHLORIDE
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- CAS-Nr.
- 82495-75-8
- Englisch Name:
- 2-(TRIMETHYLSILYL)ETHOXYMETHYLTRIPHENYLPHOSPHONIUM CHLORIDE
- Synonyma:
- PHENYL PHOSPHONIUM CHLORIDE;SEM-TRIPHENYLPHOSPHONIUM CHLORIDE;triphenyl(2-trimethylsilylethoxymethyl)phosphanium;[2-(trimethylsily)ethoxymethyl]triphenylphosphonium.Cl;2-(trime-silyl)ethoxymethyl-triphenyl-phosphonium chloride;-(Trimethylsilyl)ethoxymethyl-triphenylphosphonium chloride;2-(TRIMETHYLSILYL)ETHOXYMETHYLTRIPHENYLPHOSPHONIUM CHLORIDE;triphenyl(2-trimethylsilylethoxymethyl)phosphanium:chloride;Triphenyl((2-(trimethylsilyl)ethoxy)methyl)phosphonium chloride;Phosphonium, triphenyl[[2-(trimethylsilyl)ethoxy]methyl]-, chloride
- CBNumber:
- CB6125466
- Summenformel:
- C24H30ClOPSi
- Molgewicht:
- 429.01
- MOL-Datei:
- 82495-75-8.mol
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2-(TRIMETHYLSILYL)ETHOXYMETHYLTRIPHENYLPHOSPHONIUM CHLORIDE Eigenschaften
- Schmelzpunkt:
- 145-149 °C(lit.)
- storage temp.
- Sealed in dry,2-8°C
- L?slichkeit
- Sol H2O and dichloromethane; sparingly soluble in
THF.
- Aggregatzustand
- powder to crystal
- Farbe
- White to Almost white
- BRN
- 4632507
- CAS Datenbank
- 82495-75-8(CAS DataBase Reference)
2-(TRIMETHYLSILYL)ETHOXYMETHYLTRIPHENYLPHOSPHONIUM CHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Physikalische Eigenschaften
mp 165–169 °C.
Verwenden
2-(Trimethylsilyl)ethoxymethyltriphenylphosphonium Chloride is used in preparation of Benzodecalindiones as antitumor agents.
synthetische
Involves reaction of triphenylphosphine
with 2-(trimethylsilyl)ethoxymethyl chloride in benzene at gentle
reflux for 18 h. Upon cooling, the resulting phosphonium salt
can be recovered by filtration and purified by triturating with
diethyl ether in 94% yield.
l?uterung methode
Wash the solid with AcOH and recrystallise it from CH2Cl2/EtOAc. Dry it in a vacuum desiccator. Hygroscopic. 1H NMR (CDCl3) : -0.2 (s, Me3Si), 0.8 (t, 8Hz, CH2Si), 3.83 (t, 8Hz, OCH2), 5.77 (d, JPH 4Hz, P+-CH2O) and 7.70 (m, aromatic H). [Sch.nauer & Zbiral Justus Liebigs Ann Chem 1039 1983.]
2-(TRIMETHYLSILYL)ETHOXYMETHYLTRIPHENYLPHOSPHONIUM CHLORIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-(TRIMETHYLSILYL)ETHOXYMETHYLTRIPHENYLPHOSPHONIUM CHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 73)Lieferanten
82495-75-8()Verwandte Suche:
- SEM-TRIPHENYLPHOSPHONIUM CHLORIDE
- 2-(TRIMETHYLSILYL)ETHOXYMETHYLTRIPHENYLPHOSPHONIUM CHLORIDE
- -(Trimethylsilyl)ethoxymethyl-triphenylphosphonium chloride
- 2-(trime-silyl)ethoxymethyl-triphenyl-phosphonium chloride
- PHENYL PHOSPHONIUM CHLORIDE
- [2-(trimethylsily)ethoxymethyl]triphenylphosphonium.Cl
- 2-(Trimethylsilyl)ethoxymethyl-triphenylphosphonium chloride,SEM-triphenylphosphonium chloride
- Phosphonium, triphenyl[[2-(trimethylsilyl)ethoxy]methyl]-, chloride
- triphenyl(2-trimethylsilylethoxymethyl)phosphanium:chloride
- Triphenyl((2-(trimethylsilyl)ethoxy)methyl)phosphonium chloride
- triphenyl(2-trimethylsilylethoxymethyl)phosphanium
- 82495-75-8
- CH33SiCH2CH2OCH2PC6H53Cl
- C24H30OPSiCl
- C24H30ClOPSi
- C-C Bond Formation
- Si-(C)4 Compounds
- Wittig Reaction
- Wittig & Horner-Emmons Reaction
- Si (Classes of Silicon Compounds)
- Silicon Compounds (for Synthesis)
- Phosphonium Compounds
- Synthetic Reagents
- Wittig Reagents
- Olefination
- Wittig Reaction
- Phosphonium Compounds
- Si (Classes of Silicon Compounds)
- Si-(C)4 Compounds
- Silicon Compounds (for Synthesis)
- Synthetic Organic Chemistry
- Wittig & Horner-Emmons Reaction
