2-Maleimido acetic acid
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- CAS-Nr.
- 25021-08-3
- Englisch Name:
- 2-Maleimido acetic acid
- Synonyma:
- 2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetic acid;NSC 266055;N-Maleoylglycine;N-MaleiMidoglycine;N,N-maleoyl-glycine;MALEIMIDOACETIC ACID;2-maleimide acetic acid;2-MALEIMIDO ACETIC ACID;N-(CarboxyMethyl)MaleiMide;2-MALEIMIDO ACETIC ACID 97%
- CBNumber:
- CB61118111
- Summenformel:
- C6H5NO4
- Molgewicht:
- 155.11
- MOL-Datei:
- 25021-08-3.mol
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2-Maleimido acetic acid Eigenschaften
- Schmelzpunkt:
- 114 °C(Solv: chloroform (67-66-3))
- Siedepunkt:
- 376.7±25.0 °C(Predicted)
- Dichte
- 1.578±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- L?slichkeit
- soluble in DMSO, Methanol
- Aggregatzustand
- powder to crystal
- pka
- 3.31±0.10(Predicted)
- Farbe
- White to Almost white
- InChI
- InChI=1S/C6H5NO4/c8-4-1-2-5(9)7(4)3-6(10)11/h1-2H,3H2,(H,10,11)
- InChIKey
- GBKPNGVKZQBPCZ-UHFFFAOYSA-N
- SMILES
- N1(CC(O)=O)C(=O)C=CC1=O
2-Maleimido acetic acid Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White to Almost white powder to crystal or Pale Yellow Solid.
Verwenden
Maleimidoacetic Acid (CAS# 25021-08-3) is a heterocyclic organic compound that has a variety of uses in organic synthesis. It contains both a maleimide and carboxylic acid functional group, making it a versatile reagent for coupling reactions with amine-containing compounds.
Application
2-Maleimido acetic acid is a maleimide-containing ligand that could be used to produce the cisplatin-based Pt(IV) complexes (OC-6-44)-diamminedichlorido(ethanolato)(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetato)platinum(IV) and (OC-6-44)-acetatodiamminedichlorido(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetato)platinum(IV). The Pt(IV) complexes are considered to act as antitumor prodrugs and their in vivo activity can be improved by exploiting drug targeting and delivery strategies[1]. In this case, conjugation between maleimide-containing Pt(IV) prodrugs and furan or furan-containing drug delivery vectors via Diels-Alder cycloaddition.
2-Maleimido acetic acid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-Maleimido acetic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 135)Lieferanten
25021-08-3()Verwandte Suche:
- 2-MALEIMIDOACETIC ACID DIHYDRATE
- N-Maleoylglycine
- 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-acetic Acid
- N-(CarboxyMethyl)MaleiMide
- N-MaleiMidoglycine
- NSC 266055
- MAA 2-Maleimido acetic acid
- 2-MALEIMIDO ACETIC ACID 97%
- 2-(2,5-dioxopyrrol-1-yl)acetic acid
- 2-Maleimido acetic acid(MAA)
- 1H-Pyrrole-1-acetic acid, 2,5-dihydro-2,5-dioxo-
- 2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetic acid
- 2-maleimide acetic acid
- 2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-acetic acid
- MALEIMIDOACETIC ACID
- 2-MALEIMIDO ACETIC ACID
- N,N-maleoyl-glycine
- 25021-08-3
- Organic Building Blocks
- Heterocycles
- Intermediates
