LY 379268 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

LY 379268 is a group II metabotropic glutamate receptors (mGlu2/3) receptor agonist (1,2). Studies have shown that LY379268 significantly attenuated cocaine-induced increases in DA in nonhuman primates.

Biologische Aktivit?t

Highly selective group II mGlu receptor agonist (EC 50 values are 2.69 and 4.48 nM for hmGlu 2 and hmGlu 3 respectively) that displays > 80-fold selectivity over group I and group III receptors. Provides protection against NMDA-mediated cell death in vitro and offers almost complete protection against CA1 hippocampal damage following global ischemia in gerbils. Orally and systemically active.

LY 379268 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

LY 379268 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3135	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15839	69
Ascent Scientific	4401179829988	customerservice@ascentscientific.co.uk	United Kingdom	279	60
Shanghai Witofly Chemical Co.,Ltd		sales@witofly.com	China	2864	52
Jinan Mingya Medical Technology Co., Ltd.	0531-85828981	864598798@qq.com	China	588	58
ShangHai Angti Biotechnology Co., Ltd.	13764913901	info@angtibio.com	China	5037	55
Hangzhou Synstar pharmaceutical Technology CO.,Ltd	0571-85361029	synstar518@163.com	China	1990	58
BOC Sciences	--	info@bocsci.com	USA	0	65

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• LY 379268
• 2-Oxabicyclo[3.1.0]hexane-4,6-dicarboxylicacid,4-amino-,(1R,4R,5S,6R)-
• (1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylicacid
• LY397268
• CS-1087
• LY 379268, Group II mGlu agonist
• 191471-52-0
• AMINOACID
• Glutamate