Physalaemin Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Physalaemin is an oligopeptide that is originally derived from the skin of the South American frog Physalaemus fuscumaculatus. It belongs to the class of kinins and shares a similar chemical structure and mode of action with Substance P. It is a potent vasodilator and has hypotensive effects.
Verwenden
Physalaemin is a neuropeptide found in amphibians that has shown potential in the treatment of Sjogren's disease.?
Einzelnachweise
[1] Grace CR, et al. Solution conformation of non-mammalian tachykinin physalaemin in lipid micelles by nuclear magnetic resonance. Biopolymers. 2011;96(3):252-9. DOI:
10.1002/bip.21519[2] Kobayashi J, Hydrolytic cleavage of pyroglutamyl-peptide bond. V. selective removal of pyroglutamic acid from biologically active pyroglutamylpeptides in high concentrations of aqueous methanesulfonic acid. Chem Pharm Bull (Tokyo). 2006 Jun;54(6):827-31. DOI:
10.1248/CPB.54.827[3] Hypotensive effect of eledoisin, physalaemin and related peptides in man DOI:
10.1007/BF00535905[4] Physalaemin Inhibits Thyrotropin Secretion in Rats DOI:
10.1055/s-0029-1210457[5] Action of Physalaemin on the Ionic Transport Across the Frog Skin: Archives of Physiology and Biochemistry: Vol 105, No DOI:
10.1055/s-0029-1210457
Physalaemin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
