NEOCARZINOSTATIN
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NEOCARZINOSTATIN Eigenschaften
- Schmelzpunkt:
- 260° (dec)
- storage temp.
- 2-8°C
- Aggregatzustand
- Liquid
- Farbe
- Colorless to light yellow
Sicherheit
Toxizit?t | LD50 in mice (mg/kg): 1050 orally, 0.96 i.v. (Toriyama) |
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NEOCARZINOSTATIN Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Neocarzinostatin was found in the culture broth of Streptomyces carzinostaticus by Ishida et al. of Tohoku University in 1957. It showed strong cytotoxicity against sarcoma 180 ascites, tumor cells, and leukemia SN36. Neocarzinostatin was found to be an acidic peptide of Mr 10700, consisting of 109 amino acid residues. Recently the principal agent of anticancer and antibacterial activity in neocarzinostatin was found to be a small molecular chromophore with the peptide component playing a role by stabilizing the chromophore in vivo. Neocarzinostatin is used to treat leukemia and gastric and pancreatic cancer.Verwenden
Neocarzinostatin from Streptomyces carzinostaticus has been used:- as a DNA damaging agent to treat human fibroblast GM0637 cells
- as a radiomimetic antibiotic to induce DNA damage
- in combination with Vγ2Vδ2 T cells to determine the cytotoxicity in ovarian cancer cells
NEOCARZINOSTATIN Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Zinc sulfate heptahydrate
Kupfersulfat
PEPTONE
BAKERS YEAST
Natriumchlorid
Sojabohnenmehl
D-Glucose monohydrate
Calciumcarbonat
MEAT EXTRACT
Mangan(II)-chlorid
Peptone
Downstream Produkte
NEOCARZINOSTATIN Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 20)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 |
contact@trustwe.com | China | 5738 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32161 | 58 |
Zhejiang Huida Biotech Co., LTD | 008613515763466 8615669048680 |
wendy@huidabiotech.com | CHINA | 87 | 58 |
T&W GROUP | 021-61551611 13296011611 |
contact@trustwe.com | China | 9895 | 58 |
Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 |
3003855609@qq.com | China | 7787 | 56 |
Chizhou Kailong Import and Export Trade Co., Ltd. | |
xg01_gj@163.com | China | 9484 | 50 |
Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51456 | 80 |
Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 |
psaitong@jm-bio.com | China | 12306 | 58 |
Zhejiang Huida Biotech Co., LTD | 0571-89903882 15990081639 |
sunshixuan@huidabiotech.com | China | 3656 | 58 |
Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; |
psaitong@jm-bio.com | China | 29774 | 58 |
- neocarcinostatin
- neocarzinostatink
- neocarzinostatin from streptomyces carzinostaticus
- NSC-157365
- Aids002003
- Aids-002003
- a8544527g1
- NEOCARZINOSTATIN FROM STREPTOMYCEC CARZINOSTATICUS
- 9014-02-2