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CP-424,174

CP-424,174 Struktur
210825-31-3
CAS-Nr.
210825-31-3
Englisch Name:
CP-424,174
Synonyma:
CP-424,174;CP-424,174 >=98% (HPLC);N-((4-Chloro-2,6-diisopropylphenyl)carbamoyl)-3-(2-hydroxypropan-2-yl)benzenesulfonamide;CP424174,IL-1β,NLRP3,Inhibitor,CP 424174,CP-424174,Inflammasome,inhibit,NOD-like Receptor (NLR);N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide;Benzenesulfonamide, N-[[[4-chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)-
CBNumber:
CB54741315
Summenformel:
C22H29ClN2O4S
Molgewicht:
452.99
MOL-Datei:
210825-31-3.mol

CP-424,174 Eigenschaften

Dichte
1?+-.0.06 g/cm3(Predicted)
storage temp. 
room temp
L?slichkeit
DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:5): 0.16 mg/ml
pka
4.67±0.10(Predicted)
Aggregatzustand
powder
Farbe
white to beige

Sicherheit

CP-424,174 Chemische Eigenschaften,Einsatz,Produktion Methoden

Biochem/physiol Actions

CP-424,174 is a cytokine release inhibitory drugs (CRID) that inhibits the post-translational processing and secretion of IL-1b in response to LPS and ATP in human monocytes. It is quite possible that similarly to CP-456,773 (termed CRID3), CP-424,174 inhibits both NLRP3 and AIM2 inflammasomes by preventing ASC oligomerisation.

CP-424,174 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

CP-424,174 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 31)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32951 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32079 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38469 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8467 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51456 80
Zhengzhou Alfachem Co.,Ltd. 0371-53778726 18003825608
 liuxiaoyan@alfachem.cn China 1956 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9806 58
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686
 sales@rechemscience.com China 2992 58
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136
 Sales@ATKchemical.com China 7045 58
  • CP-424,174
  • N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide
  • Benzenesulfonamide, N-[[[4-chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)-
  • CP-424,174 >=98% (HPLC)
  • N-((4-Chloro-2,6-diisopropylphenyl)carbamoyl)-3-(2-hydroxypropan-2-yl)benzenesulfonamide
  • CP424174,IL-1β,NLRP3,Inhibitor,CP 424174,CP-424174,Inflammasome,inhibit,NOD-like Receptor (NLR)
  • 210825-31-3
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