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N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Struktur
149649-22-9
CAS-Nr.
149649-22-9
Englisch Name:
N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE
Synonyma:
NAFADOTRIDE;Nafadotride, D3 antagonist;N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE;2-Naphthalenecarboxamide, N-[(1-butyl-2-pyrrolidinyl)methyl]-4-cyano-1-methoxy-
CBNumber:
CB5402878
Summenformel:
C22H27N3O2
Molgewicht:
365.47
MOL-Datei:
149649-22-9.mol

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Eigenschaften

Siedepunkt:
556.6±40.0 °C(Predicted)
Dichte
1.17±0.1 g/cm3(Predicted)
storage temp. 
Desiccate at RT
pka
12.84±0.46(Predicted)

Sicherheit

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Nafadotride is a highly potent and competitive dopamine D3 receptor (D3R) antagonist.

Definition

ChEBI: A naphthalenecarboxamide resulting from the formal condensation of the carboxylic acid group of 4-cyano-1-methoxynaphthalene-2-carboxylic acid with the primary amino group of 1-(1-butylpyrrolidin-2-yl]methanamine. It is a highly potent, competitive, prefer ntial dopamine D3 receptor antagonist, centrally active upon systemic administration.

Biologische Aktivit?t

Highly potent, competitive, preferential dopamine D 3 receptor antagonist. K i values are 0.52, 5, and 269 nM for human cloned D 3 , D 2 and D 4 receptors respectively. Centrally active upon systemic administration.

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 33)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
TargetMol Chemicals Inc. 		+8613564774135
 zijue.cai@tsbiochem.com United States 19884 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
ShangHai ChuanQian Chemcial Technique Centre 15869524721
 3525679403@qq.com China 4322 58
Energy Chemical 021-58432009 400-005-6266
 marketing1@energy-chemical.com China 44807 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912
 order@med-bio.cn China 8140 58
QUALITY CONTROL SOLUTIONS LTD. 0755-66853366; 13670046396
 ORDERS@QCSRM.COM China 24342 58
TargetMol Chemicals Inc. 4008200310
 marketing@tsbiochem.com China 24644 58
United States Biological --
 sales@advtechind.com United States 6075 58

149649-22-9()Verwandte Suche:

  • NAFADOTRIDE
  • N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE
  • 2-Naphthalenecarboxamide, N-[(1-butyl-2-pyrrolidinyl)methyl]-4-cyano-1-methoxy-
  • Nafadotride, D3 antagonist
  • 149649-22-9
  • C22H27N3O2
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