benzyl N-[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate:hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Z-Phe-Arg 7-amido-4-methylcoumarin hydrochloride has been used:
- as a fluorogenic substrate in actinidin inhibition assay
- as a kallikrein substrate
- as a trypsin substrate for fluorometric assay
- as a cathepsin-L substrate
Allgemeine Beschreibung
Substrate for fluorogenic assay of plasma and glandular kallikreins. Also serves as a substrate for cathepsin B, cathepsin L, and papain.
Biochem/physiol Actions
Z-Phe-Arg 7-amido-4-methylcoumarin (Z-FR-AMC) proteolytic lysis by proteases leads to the liberation of AMC resulting in increased fluorescence in the enzymatic reaction.
benzyl N-[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate:hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte