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1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one

1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one Struktur
1428774-45-1
CAS-Nr.
1428774-45-1
Englisch Name:
1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one
Synonyma:
EOS-61635;PF-06459988;PF-06459988 >=98% (HPLC);1-((3R,4R)-3-(((5-chloro-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one;irreversible,oral,T790M,Inhibitor,EGFR,PF 06459988,PF-06459988,HER1,NSCLC,inhibit,PF06459988,Epidermal growth factor receptor,cancer,ErbB-1;1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one;2-Propen-1-one, 1-[(3R,4R)-3-[[[5-chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]methyl]-4-methoxy-1-pyrrolidinyl]-
CBNumber:
CB53133463
Summenformel:
C19H22ClN7O3
Molgewicht:
431.88
MOL-Datei:
1428774-45-1.mol

1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one Eigenschaften

Dichte
1.50±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMSO : 50 mg/mL (115.77 mM)
Aggregatzustand
Solid
pka
11.26±0.50(Predicted)
Farbe
White to off-white

Sicherheit

1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one Chemische Eigenschaften,Einsatz,Produktion Methoden

1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 30)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
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Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
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HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
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InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
Jinan elephant international trading co., LTD
13006575422@163.com China 6355 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088
 3193328036@qq.com China 29785 68
Zhongshan Geometric Biological Technology Co., Ltd. +86-13168912896
China 253 58
Kaixin Chemical (Hong Kong) Limited 010-88886666-01 13112345678
 loyson@tcypharm.com China 595 55
Shanghai Biopharmaleader Co., Ltd. +86 18721201413
sales@biopharmaleader.com China 1720 58
  • 1-((3R,4R)-3-(((5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one
  • PF-06459988
  • PF-06459988 >=98% (HPLC)
  • 2-Propen-1-one, 1-[(3R,4R)-3-[[[5-chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]methyl]-4-methoxy-1-pyrrolidinyl]-
  • 1-((3R,4R)-3-(((5-chloro-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)methyl)-4-methoxypyrrolidin-1-yl)prop-2-en-1-one
  • EOS-61635
  • irreversible,oral,T790M,Inhibitor,EGFR,PF 06459988,PF-06459988,HER1,NSCLC,inhibit,PF06459988,Epidermal growth factor receptor,cancer,ErbB-1
  • 1428774-45-1
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