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BI-7273

BI-7273 Struktur
1883429-21-7
CAS-Nr.
1883429-21-7
Englisch Name:
BI-7273
Synonyma:
BI273;BI-7273;CS-2327;BI 7273;BI7273;inhibit,Inhibitor,Epigenetic Reader Domain,BI7273,BI-7273,BI 7273;4-(4-((dimethylamino)methyl)-2,6-dimethoxyphenyl)-2-methyl-2,7-naphthyridin-1(2H)-one;2,7-Naphthyridin-1(2H)-one, 4-[4-[(dimethylamino)methyl]-3,5-dimethoxyphenyl]-2-methyl-
CBNumber:
CB53128809
Summenformel:
C20H23N3O3
Molgewicht:
353.41
MOL-Datei:
1883429-21-7.mol

BI-7273 Eigenschaften

Siedepunkt:
509.2±50.0 °C(Predicted)
Dichte
1.189±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
≥35.3 mg/mL in DMSO with gentle warming; ≥1.99 mg/mL in EtOH with ultrasonic; ≥8.74 mg/mL in H2O
Aggregatzustand
solid
pka
8.32±0.28(Predicted)
Farbe
White to off-white

Sicherheit

BI-7273 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

BI-7273 is a potent BRD9 bromodomain inhibitor (Kd = 15.4 nM; IC50 = 19 nM) that less effectively inhibits the functionally and structurally related BRD7 bromodomain (IC50 = 117 nM). It is without effect against the bromodomains of BRD2 and BRD4, as well as a panel of kinases. BI-7273 inhibits the growth of EOL-1 acute myeloid leukemia cells in vitro (EC50 = 1.4 μM).

BI-7273 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

BI-7273 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 55)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32112 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
 sales@hzclap.com CHINA 6312 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471
 sales@sarms4muscle.com China 10473 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38596 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054
 trendseenbio@gmail.com China 11681 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8467 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
Shanghai Boyle Chemical Co., Ltd.
sales@boylechem.com China 2922 55
  • BI-7273
  • BI273
  • 2,7-Naphthyridin-1(2H)-one, 4-[4-[(dimethylamino)methyl]-3,5-dimethoxyphenyl]-2-methyl-
  • CS-2327
  • BI 7273;BI7273
  • inhibit,Inhibitor,Epigenetic Reader Domain,BI7273,BI-7273,BI 7273
  • 4-(4-((dimethylamino)methyl)-2,6-dimethoxyphenyl)-2-methyl-2,7-naphthyridin-1(2H)-one
  • 1883429-21-7
  • 1883429-21-9
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