4-bromo-N'-butylbenzohydrazide
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- CAS-Nr.
- 537672-41-6
- Englisch Name:
- 4-bromo-N'-butylbenzohydrazide
- Synonyma:
- UF 010;CS-2427;UF010, >98%;UF-010; UF 010;UF010 >=98% (HPLC);4-Bromo-N'-butylbenzohydrazide;4-bromo-N'-butylbenzohydrazide;4-Bromobenzoic acid 2-butylhydrazide;Benzoic acid, 4-bromo-, 2-butylhydrazide;UF010,HDAC,UF-010,UF 010,Histone deacetylases,Inhibitor,inhibit
- CBNumber:
- CB53049247
- Summenformel:
- C11H15BrN2O
- Molgewicht:
- 271.15
- MOL-Datei:
- 537672-41-6.mol
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4-bromo-N'-butylbenzohydrazide Eigenschaften
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- L?slichkeit
- insoluble in H2O; ≥10.65 mg/mL in DMSO; ≥20.85 mg/mL in EtOH
- Aggregatzustand
- solid
- Farbe
- White to off-white
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Bildanzeige (GHS) |
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Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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Sicherheit |
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4-bromo-N'-butylbenzohydrazide Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
UF010 is a class I HDAC inhibitor with IC
50 values of 0.06, 0.1, 0.5, and 1.5 μM for HDAC3, 2, 1, and 8, respectively. It is more than 6-fold selective for these class I HDACs over any additional HDACs. UF010 is reported to inhibit cancer cell proliferation with a mean GI
50 value of 2.94 μM when screened against the NCI-60 panel of cancer cell lines and functions by blocking the G
1/S phase of the cell cycle.
4-bromo-N'-butylbenzohydrazide Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-bromo-N'-butylbenzohydrazide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 78)Lieferanten
- 4-bromo-N'-butylbenzohydrazide
- UF 010
- 4-Bromobenzoic acid 2-butylhydrazide
- CS-2427
- UF-010; UF 010
- UF010, >98%
- Benzoic acid, 4-bromo-, 2-butylhydrazide
- UF010 >=98% (HPLC)
- UF010,HDAC,UF-010,UF 010,Histone deacetylases,Inhibitor,inhibit
- 4-Bromo-N'-butylbenzohydrazide
- 537672-41-6