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FC 131

FC 131 Struktur
606968-52-9
CAS-Nr.
606968-52-9
Englisch Name:
FC 131
Synonyma:
FC131,FC-131;cyclo(2Nal-Gly-D-Tyr-Arg-Arg);FC 131, CXCR4 activation inhibitor;Cyclo[3-(2-naphthalenyl)-L-alanylglycyl-D-tyrosyl-L-arginyl-L-arginyl]
CBNumber:
CB52550797
Summenformel:
C36H47N11O6
Molgewicht:
729.83
MOL-Datei:
606968-52-9.mol

FC 131 Eigenschaften

Dichte
1.45±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 1 mg/ml
pka
9.89±0.15(Predicted)
Aggregatzustand
Powder
Wasserl?slichkeit
Soluble to 2 mg/ml in water

Sicherheit

FC 131 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

C-X-C chemokine receptor 4 (CXCR4) is a receptor for the stromal cell-derived factor-1 (SDF-1) which is designated as chemokine ligand 12 (CXCL12). It is involved in cell progression, hematopoiesis, cancer, HIV entry, and rheumatoid arthritis. FC 131 is an inhibitor of CXCR4 activation by SDF-1 (IC50 = 4.5 nM) and also blocks HIV-induced cytopathogenicity (EC50 = 73 nM). FC 131 derivatives can be used for imaging CXCR4 and elucidating its function.

Verwenden

Cyclo[3-?(2-?naphthalenyl)?-?L-?alanylglycyl-?D-?tyrosyl-?L-?arginyl-?L-?arginyl] is a CXCR4 antagonist with anti-HIV properties.

FC 131 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


FC 131 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 33)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
TargetMol Chemicals Inc.
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marketing@targetmol.com United States 32161 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471
sales@sarms4muscle.com China 10473 58
Hebei Miaoyin Technology Co.,Ltd
+86-17367732028 +86-17367732028
kathy@hbyinsheng.com China 3512 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43340 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
Changsha MOL Changes Biotechnology Co., Ltd.
+8619375158599
info@molchanges.com China 5223 58
VDM Biochemicals 0330-2528181
sales@vdmbio.com United States 510 64
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632
sales@reading-chemicals.com China 15178 58
Creative Peptides
info@creative-peptides.com United States 6083 56

  • Cyclo[3-(2-naphthalenyl)-L-alanylglycyl-D-tyrosyl-L-arginyl-L-arginyl]
  • FC131,FC-131
  • cyclo(2Nal-Gly-D-Tyr-Arg-Arg)
  • FC 131, CXCR4 activation inhibitor
  • 606968-52-9
  • C36H47N11O6
  • CXCR4 antagonist.
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