5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
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- CAS-Nr.
- 133627-17-5
- Englisch Name:
- 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
- Synonyma:
- BIRH 414;BIRH 414 BS;Nevirapine EP Impurity A;Nevirapine Related CoMpound A;Nevirapine USP Related Compound A;11-Ethyl-4-methyl-5,11-dihydro-6H-d;Nevirapine Related Compound A (15 mg);Nevirapine EP Impurity A/ Nevirapine Related Compound A;11-Ethyl-5H-dipyrido[3,2-b:2'',3''-e][1,4]diazepin-6(11H)-one;11-ethyl-4-methyl-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one
- CBNumber:
- CB52539709
- Summenformel:
- C14H14N4O
- Molgewicht:
- 254.29
- MOL-Datei:
- 133627-17-5.mol
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5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Eigenschaften
- Schmelzpunkt:
- 212-214℃ (1,2-dichloroethane )
- Siedepunkt:
- 389.8±42.0 °C(Predicted)
- Dichte
- 1.224±0.06 g/cm3(Predicted)
- pka
- 12.05±0.20(Predicted)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Bildanzeige (GHS) |
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Alarmwort |
Achtung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
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P264, P270, P301+P310, P321, P330,P405, P501 |
H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
H373 |
Kann die Organe sch?digen bei l?ngerer oder wiederholter Exposition. |
Spezifische Zielorgan-Toxizit?t (wiederholte Exposition) |
Kategorie 2 |
Warnung |
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P260, P314, P501 |
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Sicherheit |
P260 |
Dampf/Aerosol/Nebel nicht einatmen. |
P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
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5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
BIRH 414 is an derivative of 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine, a highly potent inhibitor of wild-type human immunodeficiency virus type 1. BIRH 414 was also shown to exhibit binding affinity towards HIV-1 reverse transcriptase enzyme.
This is also an impurity found in Nevirapine (N391275).
5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 32)Lieferanten
- Nevirapine Related CoMpound A
- Nevirapine Related Compound A (15 mg) (5,11-dihydro-6H-11-ethyl-4-methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one)
- BIRH 414
- 11-Ethyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
- 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
- BIRH 414 BS
- Nevirapine impurity Ⅱ{11-ethyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2′,3′-e][1,4] diazepin-6-one}
- 11-Ethyl-5H-dipyrido[3,2-b:2'',3''-e][1,4]diazepin-6(11H)-one
- Nevirapine Impurit Ⅱ5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
- Nevirapine EP Impurity A/ Nevirapine Related Compound A
- Nevirapine Related Compound A (15 mg)
- 6H-Dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, 11-ethyl-5,11-dihydro-4-methyl-
- 11-Ethyl-4-methyl-5,11-dihydro-6H-d
- Nevirapine EP Impurity A
- 11-ethyl-4-methyl-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one
- Nevirapine impurity Ⅱ
{11-ethyl-4-methyl-5,11-dihydr o-6H-dipyrido[3,2-b:2′,3′
-e][1,4] diazepin-6-one}
- Nevirapine USP Related Compound A
- Nevirapine Impurit Ⅱ5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
- Nevirapine Impurit Ⅱ5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
- 11-Ethyl-4-methyl-5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
- 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
- 133627-17-5
- 25429
- Pharmaceuticals, Intermediates & Fine Chemicals