PI 828 Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

A cell-permeable LY 294002 (Cat. Nos. 440202 & 440204) 4′-amino derivative with enhanced potency against p110α/β/δ/γ (IC₅₀ in nM/-fold increase in potency = 183/2.7-, 98/5.7-, 1227/.5-, and 1967/1.9-, respectively). The molecule has been immobilized on epoxy-containing solid surface via the 4′-amine for binding studies and shown to interact with non-PI3K cellular proteins, such as mTOR, ALDH1, Brd4, GSK3β, and CKIIα.

Biologische Aktivit?t

PI 3-Kinase inhibitor (IC 50 values are 0.098, 0.183, 0.227 and 1.967 μ M for p110 β , p110 α , p110 δ and p110 γ respectively) that displays higher potency than LY 294002 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride). Can be immobilized onto a solid phase.

PI 828 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

PI 828 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32222	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	5221	58
	821-50328103-801 18930552037	3bsc@sina.com	China	15839	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8447	60
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9803	58
Shanghai YuanYe Biotechnology Co., Ltd.	021-61312847; 18021002903	3008007409@qq.com	China	71829	60
Shanghai Chaolan Chemical Technology Center	021-QQ：65489617 15618227136	Sales@ATKchemical.com	China	9342	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840 18892239720	psaitong@jm-bio.com	China	12306	58

942289-87-4()Verwandte Suche:

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• PI 828
• 2-(4-Morpholinyl)-8-(4-aminopheny)l-4H-1-benzopyran-4-one
• 8-(4-Aminophenyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one
• 8-(4-aminophenyl)-2-morpholin-4-ylchromen-4-one
• LY 294002, 4-NH - CAS 942289-87-4 - Calbiochem
• LY 294002, 4′-NH2
• PI 828,PI828
• 4H-1-Benzopyran-4-one, 8-(4-aminophenyl)-2-(4-morpholinyl)-
• 8-(4-Aminophenyl)-2-(morpholin-4-yl)-4H-chromen-4-one
• PI-828, 10 mM in DMSO
• LY 294002, 4′-NH₂
• 942289-87-4