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(R)-SLV 319

(R)-SLV 319 Struktur
656827-86-0
CAS-Nr.
656827-86-0
Englisch Name:
(R)-SLV 319
Synonyma:
(R)-SLV 319;SLV 319, (R)-(+)-;(4R)-5-(4-chlorophenyl)-N-(4-chlorophenyl)sulfonyl-N'-methyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide;4-chloro-N-{[3-(4-chloro-phenyl)-4-phenyl-4,5-dihydro-pyrazol-1-yl]-methylamino-methylene}-benzenesulfonamide;1H-Pyrazole-1-carboximidamide, 3-(4-chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4-phenyl-, (4R)-
CBNumber:
CB52453032
Summenformel:
C23H20Cl2N4O2S
Molgewicht:
487.4
MOL-Datei:
656827-86-0.mol

(R)-SLV 319 Eigenschaften

Siedepunkt:
623.2±65.0 °C(Predicted)
Dichte
1.38±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
Aggregatzustand
crystalline solid
pka
11?+-.0.60(Predicted)

Sicherheit

(R)-SLV 319 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Central cannabinoid (CB1) receptor antagonists may have potential in the treatment of a number of diseases such as neuroinflammatory disorders, cognitive disorders, septic shock, obesity, psychosis, addiction, and gastrointestinal disorders. (R)-SLV 319 is the inactive enantiomer of SLV 319 with 100-fold less affinity for the CB1 receptor. SLV 319 is a potent and selective CB1 receptor antagonist with Ki values of 7.8 and 7,943 nM for CB1 and peripheral cannabinoid (CB2) receptors, respectively. SLV 319 is less lipophilic (log P = 5.1) and therefore more water soluble than other known CB1 receptor ligands.

(R)-SLV 319 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(R)-SLV 319 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 28)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9806 58
BOC Sciences --
 info@bocsci.com USA 0 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11218 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369
3477467573@qq.com China 8617 58
Anqing Rong Chuang Biological Technology Co., Ltd. 15001988657
 1367753897@qq.com China 1003 58
TargetMol Chemicals Inc. 4008200310
 marketing@tsbiochem.com China 24644 58
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd 18162595016; 18162595016
 3287908757@qq.com China 9122 58
ApexBio Technology --
 sales@apexbt.com United States 6251 58
  • (R)-SLV 319
  • (4R)-5-(4-chlorophenyl)-N-(4-chlorophenyl)sulfonyl-N'-methyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
  • 4-chloro-N-{[3-(4-chloro-phenyl)-4-phenyl-4,5-dihydro-pyrazol-1-yl]-methylamino-methylene}-benzenesulfonamide
  • 1H-Pyrazole-1-carboximidamide, 3-(4-chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4-phenyl-, (4R)-
  • SLV 319, (R)-(+)-
  • 656827-86-0
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