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(2S)-1-[[[4-METHYL-1-(2-PYRIMIDINYL)-4-PIPERIDINYL]AMINO]ACETYL]-2-PYRROLIDINECARBONITRILE

(2S)-1-[[[4-METHYL-1-(2-PYRIMIDINYL)-4-PIPERIDINYL]AMINO]ACETYL]-2-PYRROLIDINECARBONITRILE Struktur
440100-64-1
CAS-Nr.
440100-64-1
Englisch Name:
(2S)-1-[[[4-METHYL-1-(2-PYRIMIDINYL)-4-PIPERIDINYL]AMINO]ACETYL]-2-PYRROLIDINECARBONITRILE
Synonyma:
K 579;Dipeptidyl Peptidase IV Inhibitor IV;Dipeptidylpeptidase IV Inhibitor IV, K579;Dipeptidylpeptidase IV Inhibitor IV, K579 - CAS 440100-64-1 - Calbiochem;(S)-1-(4-Methyl-1-(2-pyrimidinyl)-4-piperidylamino)acetyl-2-pyrrolidinecarbonitrile;(2S)-1-[2-[(4-methyl-1-pyrimidin-2-yl-4-piperidyl)amino]acetyl]pyrrolidine-2-carbonitrile;(2S)-1-[[[4-METHYL-1-(2-PYRIMIDINYL)-4-PIPERIDINYL]AMINO]ACETYL]-2-PYRROLIDINECARBONITRILE;2-Pyrrolidinecarbonitrile, 1-[2-[[4-methyl-1-(2-pyrimidinyl)-4-piperidinyl]amino]acetyl]-, (2S)-
CBNumber:
CB52448579
Summenformel:
C17H24N6O
Molgewicht:
328.41
MOL-Datei:
440100-64-1.mol

(2S)-1-[[[4-METHYL-1-(2-PYRIMIDINYL)-4-PIPERIDINYL]AMINO]ACETYL]-2-PYRROLIDINECARBONITRILE Eigenschaften

storage temp. 
2-8°C
L?slichkeit
Soluble to 50 mM in 1eq. HCl and to 100 mM in DMSO
Aggregatzustand
solid
Farbe
Off-white to light yellow

Sicherheit

WGK Germany  3

(2S)-1-[[[4-METHYL-1-(2-PYRIMIDINYL)-4-PIPERIDINYL]AMINO]ACETYL]-2-PYRROLIDINECARBONITRILE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

K 579 is a slow-binding inhibitor of dipeptidyl peptidase IV and a long-acting hypoglycemic agent.

Allgemeine Beschreibung

Dipeptidyl Peptidase IV Inhibitor IV, also known as K579 ((S)-1-[4-methyl-1-(2-pyrimidinyl)-4-piperidylamino]acetyl-2-pyrrolidinecarbonitrile), is orally available. It has a formula weight of 339.39 g/mol.

Biologische Aktivit?t

Dipeptidyl peptidase IV inhibitor. Inhibits rat, canine, human and monkey enzymes with IC 50 values of 3, 5, 8, and 8 nM respectively. Long-acting hypoglycemic agent; attenuates glucose excursion following glucose loading in Zucker fatty rats.

(2S)-1-[[[4-METHYL-1-(2-PYRIMIDINYL)-4-PIPERIDINYL]AMINO]ACETYL]-2-PYRROLIDINECARBONITRILE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(2S)-1-[[[4-METHYL-1-(2-PYRIMIDINYL)-4-PIPERIDINYL]AMINO]ACETYL]-2-PYRROLIDINECARBONITRILE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 31)Lieferanten
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TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
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Aladdin Scientific 		+1-+1(833)-552-7181
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TargetMol Chemicals Inc. 		+8613564774135
 zijue.cai@tsbiochem.com United States 19881 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51456 80
EMMX Biotechnology LLC 888-539-0666
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BOC Sciences --
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MedBioPharmaceutical Technology Inc 021-69568360 18916172912
 order@med-bio.cn China 8140 58
TargetMol Chemicals Inc. 4008200310
 marketing@tsbiochem.com China 24644 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581
 sales@chemhifuture.com China 5018 58
  • (2S)-1-[[[4-METHYL-1-(2-PYRIMIDINYL)-4-PIPERIDINYL]AMINO]ACETYL]-2-PYRROLIDINECARBONITRILE
  • K 579
  • (S)-1-(4-Methyl-1-(2-pyrimidinyl)-4-piperidylamino)acetyl-2-pyrrolidinecarbonitrile
  • Dipeptidyl Peptidase IV Inhibitor IV
  • Dipeptidylpeptidase IV Inhibitor IV, K579
  • (2S)-1-[2-[(4-methyl-1-pyrimidin-2-yl-4-piperidyl)amino]acetyl]pyrrolidine-2-carbonitrile
  • Dipeptidylpeptidase IV Inhibitor IV, K579 - CAS 440100-64-1 - Calbiochem
  • 2-Pyrrolidinecarbonitrile, 1-[2-[[4-methyl-1-(2-pyrimidinyl)-4-piperidinyl]amino]acetyl]-, (2S)-
  • 440100-64-1
  • C17H24N6O
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