LY 367385 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

LY 367385 is a selective mGlu1a receptor antagonist used to treat inflammatory diseases (ie. multiple sclerosis) and neurodegenerative diseases (ie. Alzheimer’s) (1,2).

Biologische Aktivit?t

A selective mGlu 1a receptor antagonist, with an IC 50 value of 8.8 μ M for blockade of quisqualate-induced phosphoinositide hydrolysis vs. > 100 μ M for mGlu 5a , and negligible action on group II and III receptors. Also available as part of the Group I mGlu Receptor Tocriset™ .

Biochem/physiol Actions

LY-367385 hydrochloride has an ability to inhibit induction of long-term potentiation (LTP).

LY 367385 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

LY 367385 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8467	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52924	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15839	69
Ascent Scientific	4401179829988	customerservice@ascentscientific.co.uk	United Kingdom	279	60
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51456	80
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8447	60
BOC Sciences	--	info@bocsci.com	USA	0	65
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9409	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8140	58

198419-91-9()Verwandte Suche:

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• (S)-(+)-ALPHA-AMINO-4-CARBOXY-2-METHYLBENZENEACETIC ACID
• LY 367385
• (S)-(+)-α-Amino-4-carboxy-2-methylbenzeneaceticacid
• (S)-4-[aMino(carboxy)Methyl]-3-Methylbenzoic acid
• (S)-(+)-a-amino-4-carboxy-2-methylbenzeneacetic acid
• LY-367385 hydrochloride
• (R)-(+)-alpha-Amino-4-carboxy-2-methylbenzeneacetic acid
• LY-367385;(R)-(+)-ALPHA-AMINO-4-CARBOXY-2-METHYLBENZENEACETIC ACID
• (S)-(+)-α-Amino-4-carboxy-2-methylbenzeneacetic acid
• Benzeneacetic acid, α-amino-4-carboxy-2-methyl-, (αS)-
• SGIKDIUCJAUSRD-QMMMGPOBSA-N
• LY367385,LY-367385
• Benzeneacetic acid, α-amino-4-carboxy-2-methyl-, (αS)-
• 4-[(R)-amino(carboxy)methyl]-3-methylbenzoic acid
• 4-[(S)-amino(carboxy)methyl]-3-methylbenzoic acid
• LY 367385, mGlu1a antagonist
• 198419-91-9
• Glutamate