Zinkdi(acetat) Dihydrat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
R36:Reizt die Augen.
R50/53:Sehr giftig für Wasserorganismen, kann in Gew?ssern l?ngerfristig sch?dliche Wirkungen haben.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S60:Dieses Produkt und sein Beh?lter sind als gef?hrlicher Abfall zu entsorgen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
Zinc acetate dihydrate Zn(C2H3O2)•2H2O is a Colourless or white efflorescent crystals; faint acetic acid odor; astringent taste; monoclinic crystals; density 1.735 g/cm3; loses water at 100°C; decomposes at 237°C; readily dissolves in water, 43g/100 mL at 20°C; soluble in alcohol.
Verwenden
Zinc acetate dihydrate is used in the preparation of layered Zn-arylphosphonates with potential application in sorption, ion exchange or catalysis and zinc sulfide nanoparticles coated on silica particles. It is used in dietary and medical applications. It is also used as lozenges for treating the common cold. It is used as a seeding material to grow zinc oxide nanorods on the microfibers of polyethylene terephthalate fabric. In addition, it finds application as wood preservation, production of other zinc salts, ethylene acetate manufacture, and an analytical reagent in various industries. As a plating inhibitor, it is used in nuclear power plant.
Vorbereitung Methode
Zinc acetate is synthesized by reacting zinc oxide with glacial acetic
acid, with subsequent crystallization, separation by centrifugation,
and drying and milling of the crystals. No organic solvents are used
during the synthesis.
Allgemeine Beschreibung
Structure of zinc acetate dehydrate is monoclinic with unit cell dimensions a=14.50, b=5.32 and c=11.02?.
Pharmazeutische Anwendungen
Zinc acetate has been used as an excipient in a variety of
pharmaceutical formulations including topical gels, lotions, and
solutions, and subcutaneous injections. It has also been investigated
for use in an oral controlled-release formulation for water-soluble
drugs in combination with sodium alginate and xanthan gum.
Therapeutically, zinc acetate has been used in oral capsules for
the treatment of Wilson’s disease. Zinc acetate has also been
demonstrated to be effective as a spermicide in vaginal contraceptives.
Sicherheit(Safety)
Zinc acetate is used in topical pharmaceutical formulations and
subcutaneous injections, where it is generally regarded as relatively
nontoxic and nonirritant when used as an excipient. However, zinc
acetate is poisonous by intravenous and intraperitoneal routes; it is
also moderately toxic following oral consumption.
LD50 (mouse, IP): 0.108 g/kg
LD50 (mouse, oral): 0.287 g/kg
LD50 (rat, IP): 0.162 g/kg
LD50 (rat, oral): 0.794 g/kg
Lager
Zinc acetate loses water of hydration above 100℃. Zinc acetate
should be stored in an airtight container in a cool, dry, place.
l?uterung methode
It crystallises (in poor yield) from hot water or, better, from EtOH. [Beilstein 2 III 193, 2 IV 114.]
Inkompatibilit?ten
Zinc acetate is incompatible with oxidizing agents, zinc salts, alkalis
and their carbonates, oxalates, phosphates, and sulfides.
Regulatory Status
Included in the FDA Inactive Ingredients Database (SC injections;
topical lotions and solutions). Included in medicines licensed in the
UK.
Zinkdi(acetat) Dihydrat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
