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(2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid

(2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid Struktur
5746-03-2
CAS-Nr.
5746-03-2
Englisch Name:
(2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid
Synonyma:
CEL (>70% purity);Loratadine Impurity 71;Nε-(Carboxyethyl)lysine;N-6-(Carboxyethyl)-L-lysine;N(6)-(1-carboxyethyl)lysine;Nε-(1-Carboxyethyl)-L-lysine;L-Lysine, N6-(1-carboxyethyl)-;N-[(5S)-5-amino-5-carboxypentyl]-DL-alanine;(2S)-2-amino-6-(1-carboxyethylamino)hexanoic acid;Nμ-(1-Carboxyethyl)-L-lysine\n(Mixture of Diastereomers)
CBNumber:
CB51112970
Summenformel:
C9H18N2O4
Molgewicht:
218.25
MOL-Datei:
5746-03-2.mol

(2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid Eigenschaften

Siedepunkt:
427.7±45.0 °C(Predicted)
Dichte
1?+-.0.06 g/cm3(Predicted)
L?slichkeit
Water: Slightly Soluble
Aggregatzustand
A solid
pka
2.30±0.10(Predicted)

Sicherheit

(2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Nε-(1-Carboxyethyl)-L-lysine (CEL) is an advanced glycation end product (AGE) produced by the reaction of methyl glyoxal with lysine residues in proteins. Protein bound, but not free, CEL binds to the receptor for AGEs (RAGE). CEL levels are elevated in the lens of diabetic patients with cataract. Long-term caloric restriction decreases CEL levels in rat heart mitochondria. It decreases glutamate uptake and secretion of S100B in rat hippocampal slices in a RAGE-independent manner when used at a concentration of 1 mM.

Verwenden

CEL and CML are two stable, nonenzymatic chemical modifications of protein lysine residues resulting from glycation and oxidation reactions.

(2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 18)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939
 shenlinxing@macklin.cn China 16166 55
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656
 greensnown@163.com China 9906 50
Shenzhen Regent Biochemical Technology Co., Ltd. 0755-0755-85201366 18938635012
 sales@regentsciences.com China 9353 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11217 58
ShangHai Anpel Co, Ltd. 18501792038; 18501792038
 shanpel@anpel.com.cn China 9611 58
Energy Chemical 021-58432009 400-005-6266
 marketing@energy-chemical.com China 44918 58
TCI (Shanghai) Chemical Trading Co., Ltd. 021-021-61109150
sales@tcisct.com China 31121 58
LGC Science (Shanghai) Ltd. 17717235263
 cindy.yang@lgcgroup.com China 15583 58
Shanghai Haohong Scientific Co., Ltd. 400-400-8210725
malulu@leyan.com China 39990 58
  • N(6)-(1-carboxyethyl)lysine
  • Nε-(1-Carboxyethyl)-L-lysine
  • (2S, 1'R)/(2S, 1'S)-2-Amino-6-(1'-carboxy-ethylamino)-he xanoic acid
  • Nμ-(1-Carboxyethyl)-L-lysine\n(Mixture of Diastereomers)
  • L-Lysine, N6-(1-carboxyethyl)-
  • N-6-(Carboxyethyl)-L-lysine
  • (2S)-2-amino-6-(1-carboxyethylamino)hexanoic acid
  • CEL (>70% purity)
  • Loratadine Impurity 71
  • N-[(5S)-5-amino-5-carboxypentyl]-DL-alanine
  • Nε-(1-Carboxyethyl)-L-lysine_x000b_(Mixture of Diastereomers)
  • Nε-(Carboxyethyl)lysine
  • 5746-03-2
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