Fluorinated VHL spy molecule 3 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Fluorinated VHL Spy Molecule 3 can be used for the discovery of new von Hippel-Lindau (VHL) binders. Based on VH032 (cat# 901490), this reporter was designed in the lab of Alessio Ciulli to bind the hydroxyproline (Hyp) recognition site of VHL. When used in competition ligand-observed 19F NMR screening experiments, its displacement indicates binding by another molecule. Additional Fluorinated VHL Spy Molecules are available as listings 909416, 909432, and 909459.
The E3 ligase VHL is of growing interest for targeted protein degradation, and these spy molecules will facilitate the identification of novel VHL ligands and VHL-based degraders.

Fluorinated VHL spy molecule 3 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Fluorinated VHL spy molecule 3 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51456	80
Jilin Province Woda Biotechnology Co., Ltd.	13504435624	1927928688@qq.com	China	1471	58
Changzhou Bojia Biomedical Technology Co., Ltd.	2122619822	czbjpharma@126.com	China	18478	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054 13417589054	trendseenbio@gmail.com	China	9070	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	400-6206333 1316706386	anhua.mao@aladdin-e.com	China	48459	58

---

• Fluorinated VHL spy molecule 3
• 2-Pyrrolidinecarboxamide, 4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-(2,2,2-trifluoroacetyl)-, (2S,4R)-
• (2S,4R)-4-Hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)-1-(2,2,2-trifluoroacetyl)pyrrolidine-2-carboxamide
• (2S,4R)-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}-1-(2,2,2-trifluoroacetyl)pyrrolidine-2-carboxamide
• 2290526-29-1