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Endothelin-1 (human, porcine)

Endothelin-1 (human, porcine) Struktur
117399-94-7
CAS-Nr.
117399-94-7
Englisch Name:
Endothelin-1 (human, porcine)
Synonyma:
Endothelin;ET-1;ENDOTHELIN 1;ET-1, HUMAN;Endothelin 1【pig】;Endotherin 1【rat】;ENDOTHELIN-1(HUMAN);Endotherin 1【mouse】;ET-1, HUMAN, PORCINE;Endothelin 1【canine】
CBNumber:
CB4706533
Summenformel:
C109H159N25O32S5
Molgewicht:
2491.9
MOL-Datei:
117399-94-7.mol

Endothelin-1 (human, porcine) Eigenschaften

Siedepunkt:
2467.3±65.0 °C(Predicted)
Dichte
1.273±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
L?slichkeit
1% acetic acid: >1 mg/mL
Aggregatzustand
powder
Farbe
white
Wasserl?slichkeit
Soluble in water.
Merck 
13,3610
InChIKey
ZUBDGKVDJUIMQQ-UHFFFAOYSA-N

Sicherheit

WGK Germany  3
RTECS-Nr. KE9446500
3-10
HS Code  2937190000

Endothelin-1 (human, porcine) Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Endothelin-1 (human, porcine) has been used for coating wells in polystyrene ELISA plates. Potent agonist for ETA and ETB endothelia receptors. Induces the production of hypoxia-inducible factor 1α, and, thus, the production of VEGF.

Application

Endothelin-1 (human, porcine) has been used:
to study its effects on the production of erythropoietin under normoxia and carbon monoxide-induced hypoxia in rat models.
as a protein kinase C (PKC) agonist to study its effects on the phosphorylation of myofilament proteins in rat myocytes.
to induce a hypertrophic-like state to study its effects on contraction pressure in normal and mutated human induced pluripotent stem cells (hiPSC)-derived cardiomyocytes.
in vitro hydrolysis products of macroendothelin-1, a precursor of endothelin-1, and their pharmacodynamic properties in rabbits.
as a receptor for endothelin-1 and its role in G protein-mediated signal transduction Research.

Biologische Funktion

Endothelins are a family of vasoactive peptides secreted by endothelial cells. The three major endothelin peptides are all composed of 21 amino acids. Endothelins are the most potent vasoconstrictors known. Contraction of vascular smooth muscle in response to endothelin is associated with an increase in intracellular calcium. Increases in endothelin levels have been reported in patients with vasospastic, hypoxic, and ischemic diseases.The two identified isoforms of endothelin receptors have differing affinity for the three endothelin peptides. Selective and nonselective endothelin receptor antagonists are in development for potential use in the treatment of hypertension and other disorders associated with increased vascular resistance.

Biochem/physiol Actions

Potent agonist for ETA and ETB endothelin receptors. Induces the production of hypoxia-inducible factor 1α, and, thus, the production of VEGF.

Endothelin-1 (human, porcine) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Endothelin-1 (human, porcine) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 178)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
BOC Sciences
16314854226; +16314854226
inquiry@bocsci.com United States 19741 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21639 55
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715
admin@nexconn.com China 10310 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58
Shaanxi Pioneer Biotech Co., Ltd .
+8613259417953
sales@pioneerbiotech.com China 3000 58
Cellmano Biotech Limited
0551-65326643 18156095617
info@cellmano.com China 1000 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29815 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196
sale04@alfachem.cn China 13486 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32002 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226
sales@hzclap.com CHINA 6312 58

117399-94-7()Verwandte Suche:


  • ET-1, HUMAN
  • ET-1, HUMAN AND PORCINE
  • ET-1 (HUMAN, BOVINE, DOG, MOUSE, PORCINE, RAT)
  • ET-1 (HUMAN, MOUSE, RAT, PIG, BOVINE, DOG)
  • ET-1, HUMAN, PORCINE
  • ET-1 (HUMAN, PORCINE, DOG, RAT)
  • ENDOTHELIN-I, HUMAN, PORCINE
  • ENDOTHELIN 1, DOG, HUMAN, PORCINE, RAT
  • ENDOTHELIN-1(HUMAN)
  • ENDOTHELIN 1, HUMAN AND PORCINE
  • ENDOTHELIN-1 (HUMAN, BOVINE, DOG, MOUSE, PORCINE, RAT)
  • ENDOTHELIN-1 (HUMAN, MOUSE, RAT, PIG, BOVINE, DOG)
  • ENDOTHELIN 1 HUMAN, PORCINE
  • ENDOTHELIN-1 (HUMAN) (PORCINE, CANINE, RAT, MOUSE, BOVINE)
  • ENDOTHELIN-1 (HUMAN, PORCINE, DOG, RAT)
  • ENDOTHELIN-1 HUMAN, PORCINE, RAT, CANINE, MURINE
  • CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP
  • CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP HUMAN, PORCINE, RAT, CANINE, MURINE
  • CSCSSLMDKECVYFCHLDIIW
  • CSCSSLMDKECVYFCHLDIIW (DISULFIDE BRIDGE: 1-15 AND 3-11)
  • H-CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
  • H-CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH (DISULFIDE BRIDGE: 1-15 AND 3-11)
  • H-CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH, (DISULFIDE BONDS BETWEEN CYS1 AND CYS15/CYS3 AND CYS11)
  • M.W. 2491.90 C109H159N25O32S5
  • Endothelin 1【canine】
  • Endothelin 1【pig】
  • Endotherin 1【mouse】
  • Endotherin 1【rat】
  • CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR- PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP(DISULFIDE BRIDGE:CYS1-CYS15, CYS3-CYS11)
  • ENDOTHELIN-1 ACETATE
  • Endothelin-1 (huMan, bovine, dog, Mouse, porcine, rat) ET-1 (huMan, bovine, dog, Mouse, porcine, rat)
  • Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridges Cys1-Cys15 and Cys3-Cys11)
  • H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH acetate salt (Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11)
  • Endothelin 1 (swine, human)
  • ENDOTHELIN 1, HUMAN, PORCINE, 50 UG*
  • Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem
  • Endothelin 1, ≥97.0%(HPLC)
  • Endothelin 1 (swine)
  • ENDOTHELIN 1 HUMAN, PORCINE USP/EP/BP
  • High purity CAS 117399-94-7 ENDOTHELIN 1 HUMAN, PORCINE
  • Endothelin 1 (swine, human) acetate
  • human) acetate(117399-94-7 free base)
  • ET-1
  • ENDOTHELIN 1
  • Endothelin
  • (3S,6S,9S,12S,15S,18S)-3-((1H-Imidazol-4-yl)methyl)-18-((1H-indol-3-yl)methyl)-1-((1R,4S,7S,10S,13S,16S,19S,22S,25R,28S,31R,36R,39R,42S,45S)-31-amino-7-(4-aminobutyl)-39-benzyl-4-(2-carboxyethyl)-10-(carboxymethyl)-42-(4-hydroxybenzyl)-19,22,28-tris(hydroxymethyl)-16-isobutyl-45-isopropyl-13-(2-(methylthio)ethyl)-3,6,9,12,15,18,21,24,27,30,38,41,44,47-tetradecaoxo-33,34,49,50-tetrathia-2,5,8,11,14,17,20,23,26,29,37,40,43,46-tetradecaazabicyclo[23.22.4]henpentacontan-36-yl)-12,15-di((S)-sec-butyl
  • EDN1 Acitive Peptide
  • Rabbit Anti-ET-1 antibody
  • Rabbit Anti-Big endothelin-1 antibody
  • Endothelin 1,acetate salt
  • Mouse Anti-ET-1(2C4) antibody
  • 117399-94-7
  • C109H159O32N25S5
  • C109H159N25O32S5
  • 多肽抗原
  • Cell Signaling Enzymes
  • Biochemicals and Reagents
  • Application Index
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