CANDESARTAN-D4
|
|
|
- CAS-Nr.
- 1346604-70-3
- Englisch Name:
- CANDESARTAN-D4
- Synonyma:
- CV-11974-d4;CANDESARTAN-D4;[2H4]-Candesartan;Candesartan M1-d4;Candesartan D4 (CV-11974 D4);2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1-(phenyl-d4)-1'-phenyl]-4-yl]Methyl]-1H-benziMidazole-7-carboxylic Acid;1-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl-2,3,5,6-d4)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid;2-ethoxy-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)(2,3,5,6-2H?)-[1,1'-biphenyl]-4-yl]methyl}-1H-1,3-benzodiazole-7-carboxylic acid;Candesartan D4Q: What is
Candesartan D4 Q: What is the CAS Number of
Candesartan D4 Q: What is the storage condition of
Candesartan D4
- CBNumber:
- CB4477701
- Summenformel:
- C24H16D4N6O3
- Molgewicht:
- 444.48
- MOL-Datei:
- Mol file
|
CANDESARTAN-D4 Eigenschaften
- Schmelzpunkt:
- 151-157°C
- storage temp.
- -20°C Freezer
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly, Heated)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
|
| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H360 |
Kann die Fruchtbarkeit beeintr?chtigen oder das Kind im Mutterleib sch?digen. |
Fertility (Fruchtbarkeit) |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS08.jpg" width="20" height="20" /> |
|
|
| Sicherheit |
| P201 |
Vor Gebrauch besondere Anweisungen einholen. |
| P202 |
Vor Gebrauch alle Sicherheitshinweise lesen und verstehen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P308+P313 |
BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen. |
| P405 |
Unter Verschluss aufbewahren. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
|
CANDESARTAN-D4 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Candesartan-d
4 is intended for use as an internal standard for the quantification of candesartan by GC- or LC-MS. Candesartan is an antagonist of the angiotensin II type 1 (AT
1) receptor (K
is = 0.17, 0.12, and 0.12 nM for human AT
1, rat AT
1A, and rat AT
1B recombinant receptors, respectively) and an active metabolite of the prodrug candesartan cilexitil (Item No.
10489). It is selective for AT
1 over AT
2 receptors (K
i = 26,500 nM for the human recombinant AT
2 receptor). It inhibits angiotensin II-induced contraction of isolated rabbit aortic strips and increases in blood pressure in rats following intravenous administration (ID
50 = 0.033 mg/kg). Formulations containing candesartan have been used in the treatment of hypertension and heart failure.
Chemische Eigenschaften
CANDESARTAN-D4 is White to Off-White Solid
Verwenden
CANDESARTAN-D4 is an angiotensin II type-1 receptor antagonist. Used in treatment of congestive heart failure. Antihypertensive.
CANDESARTAN-D4 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
CANDESARTAN-D4 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 58)Lieferanten
1346604-70-3()Verwandte Suche:
- 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1-(phenyl-d4)-1'-phenyl]-4-yl]Methyl]-1H-benziMidazole-7-carboxylic Acid
- Candesartan M1-d4
- CV-11974-d4
- CANDESARTAN-D4
- [2H4]-Candesartan
- Candesartan D4Q: What is
Candesartan D4 Q: What is the CAS Number of
Candesartan D4 Q: What is the storage condition of
Candesartan D4
- Candesartan D4 (CV-11974 D4)
- 1-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl-2,3,5,6-d4)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid
- 2-ethoxy-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)(2,3,5,6-2H?)-[1,1'-biphenyl]-4-yl]methyl}-1H-1,3-benzodiazole-7-carboxylic acid
- 1346604-70-3
- C24H16D4N6O3
- Aromatics
- Bases & Related Reagents
- Intermediates & Fine Chemicals
- Isotope Labelled Compounds
- Nucleotides
- Pharmaceuticals
