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Dotinurad

Dotinurad Struktur
1285572-51-1
CAS-Nr.
1285572-51-1
Englisch Name:
Dotinurad
Synonyma:
Dotinurad;Dotinurad (FYU-981);3-(3,5-dichloro-4-hydroxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole;(3,5-Dichloro-4-hydroxyphenyl)(1,1-dioxido-3(2H)-benzothiazolyl)methanone;(3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone;Methanone, (3,5-dichloro-4-hydroxyphenyl)(1,1-dioxido-3(2H)-benzothiazolyl)-;uricosuric,Inhibitor,Dotinurad,URAT1,urate,reabsorption,SLC22A12,Urate transporter 1,inhibit,transporter
CBNumber:
CB44667832
Summenformel:
C14H9Cl2NO4S
Molgewicht:
358.2
MOL-Datei:
1285572-51-1.mol

Dotinurad Eigenschaften

Schmelzpunkt:
188 - 191°C
Siedepunkt:
614.8±55.0 °C(Predicted)
Dichte
1.662±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
L?slichkeit
Chloroform (Slightly, Sonicated), DMSO (Sparingly)
pka
4.60±0.25(Predicted)
Aggregatzustand
Solid
Farbe
White to Off-White
InChI
InChI=1S/C14H9Cl2NO4S/c15-9-5-8(6-10(16)13(9)18)14(19)17-7-22(20,21)12-4-2-1-3-11(12)17/h1-6,18H,7H2
InChIKey
VOFLAIHEELWYGO-UHFFFAOYSA-N
SMILES
C(C1=CC(Cl)=C(O)C(Cl)=C1)(N1C2=CC=CC=C2S(=O)(=O)C1)=O

Sicherheit

Dotinurad Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Dotinurad is an organic compound with the chemical Name (3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone. This compound is a newer urate-lowering agent that suppresses uric acid reabsorption through the selective inhibition of urate transporter 1 (URAT1) in the proximal renal tubules, and it was first approved in Japan in 2020 for the treatment of hyperuricemia, irrespective of gout[1].

Verwenden

Dotinurad is a useful drug for treating hyperuricemia and gout.

Dotinurad Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Dotinurad Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 96)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
+86-18600796368 +86-18600796368
 sales@sjar-tech.com China 462 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439
 sales@nextpeptide.com China 19908 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd. 		+86-029-86185165 +8618629664246
 guoyuan@eastchinapharm.com China 1615 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49734 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8617865335152
 Mandy@hangyubiotech.com China 10986 58
Protheragen-ING 		+16313385890
 info@protheragen-ing.com United States 3868 58
Arizest(Shanghai)Pharmatech Co., Ltd 		+86-021-60753300
3652837972@qq.com China 220 58
Moxin Chemicals 		+8617320513646
 mike@molcoo.com China 9457 58
  • Dotinurad
  • Methanone, (3,5-dichloro-4-hydroxyphenyl)(1,1-dioxido-3(2H)-benzothiazolyl)-
  • Dotinurad (FYU-981)
  • (3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone
  • uricosuric,Inhibitor,Dotinurad,URAT1,urate,reabsorption,SLC22A12,Urate transporter 1,inhibit,transporter
  • (3,5-Dichloro-4-hydroxyphenyl)(1,1-dioxido-3(2H)-benzothiazolyl)methanone
  • 3-(3,5-dichloro-4-hydroxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole
  • 1285572-51-1
  • API
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