LMPTP inhibitor1
|
|
|
- CAS-Nr.
- 1908414-82-3
- Englisch Name:
- LMPTP inhibitor1
- Synonyma:
- CS-2789;MDK4823;MDK 4823;MDK-4823;LMPTP-IN23;LMPTP-IN 23;INVIVO-4823;LMPTP-IN-23;LMPTP inhibitor1;LMW-PTP Inhibitor I
- CBNumber:
- CB44629485
- Summenformel:
- C28H36N4O
- Molgewicht:
- 444.61
- MOL-Datei:
- 1908414-82-3.mol
|
LMPTP inhibitor1 Eigenschaften
- Siedepunkt:
- 657.7±55.0 °C(Predicted)
- Dichte
- 1.121±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- L?slichkeit
- DMF: 20mg/mL,DMSO: 10mg/mL,Ethanol: 15mg/mL,PBS (pH 7.2): 3mg/mL
- pka
- 9.48±0.10(Predicted)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
LMPTP inhibitor1 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
LMW-PTP inhibitor I is an inhibitor of low molecular weight phosphotyrosine protein phosphatase A (LMW-PTPA; IC
50 = 0.8 μM). It is selective for LMW-PTPA over a panel of 15 protein tyrosine phosphatases but does inhibit LMW-PTPB activity by greater than 50% at 40 μM. LMW-PTP inhibitor I increases insulin-induced insulin receptor phosphorylation in HepG2 cells when used at a concentration of 10 μM. It improves glucose tolerance and decreases fasting plasma insulin levels in a mouse model of diet-induced obesity when administered at a dose of 50 mg/kg per day.
LMPTP inhibitor1 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
LMPTP inhibitor1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 17)Lieferanten
- LMPTP inhibitor1
- LMPTP INHIBITOR COMPOUND 1
- CS-2789
- LMPTP inhibitor-Compound 23
- MLS-0322825 Cmpd 23
- LMW-PTP Inhibitor I
- INVIVO-4823
- NN-Diethyl-4-[4-[[3-(1-piperidinyl)propyl]amino]-2-quinolinyl]benzamide
- LMPTP-IN 23
- LMPTP-IN23
- LMPTP-IN-23
- MDK 4823
- MDK4823
- MDK-4823
- Benzamide, N,N-diethyl-4-[4-[[3-(1-piperidinyl)propyl]amino]-2-quinolinyl]-
- N,N-diethyl-4-(4-{[3-(piperidin-1-yl)propyl]amino}quinolin-2-yl)benzamide
- 1908414-82-3
