1-Oleoyl lysophosphatidic acid sodium salt Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Oleoyl-L-α-lysophosphatidic Acid reduces the organ injury caused by endotoxemia in the rat.?It may be useful in the treatment of shock of various etiologies.
Allgemeine Beschreibung
Lysophosphatidic acid (LPA) is an essential metabolite for membrane biosynthesis. LPA interacts with the G protein-coupled receptors (GPCRs), called the LPA receptor and mediates signaling. Oleoyl-L-α-lysophosphatidic acid activates the receptor LPA4. In keratinocytes, oleoyl-L-α-lysophosphatidic acid promotes growth to some extent.
Biochem/physiol Actions
Endogenous agonist for LPA1 and LPA2 receptors. LPA does not induce angiogenesis, but has effects on endothelial cell physiology that are similar to those of sphingosine 1-phosphate. Induces cell migration of cancer and non-cancer cells.
1-Oleoyl lysophosphatidic acid sodium salt Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte