4-[(4-Methoxy-6-methylsalicyloyl)oxy]-6-methylsalicylsure Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Evernic acid is a secondary metabolite produced by some species of lichen that can bind to allosteric sites on the protein surface of FAS-II enzymes and produce antibacterial and antiplasmodial effects. It inhibits two key plasmodial FAS-II enzymes
PfFabZ and
PfFabI (IC
50 = 10.7 and 36.1 μM, respectively) but shows low efficacy against the malaria parasite
P. berghei (IC
50 = 77.3 μM).
4-[(4-Methoxy-6-methylsalicyloyl)oxy]-6-methylsalicylsure Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte