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GDC-0077

GDC-0077 Struktur
2060571-02-8
CAS-Nr.
2060571-02-8
Englisch Name:
GDC-0077
Synonyma:
CPD1573;RG 6114;GDC-0077;RO 7113755;Inavolisib;GDC-0077 Inavolisib;Inavolisib (GDC-0077);GDC-0077; RG 6114; RO 7113755;Inavolisib (Synonyms: GDC-0077;Inavolisib (RG-6114, RO-7113755)
CBNumber:
CB43175543
Summenformel:
C18H19F2N5O4
Molgewicht:
407.37
MOL-Datei:
2060571-02-8.mol

GDC-0077 Eigenschaften

Siedepunkt:
698.0±65.0 °C(Predicted)
Dichte
1.63±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMSO:110.0(Max Conc. mg/mL);245.47(Max Conc. mM)
pka
15.89±0.50(Predicted)
Aggregatzustand
Solid
Farbe
Off-white to yellow
InChIKey
SGEUNORSOZVTOL-CABZTGNLSA-N
SMILES
C(N)(=O)[C@@H](NC1C=C2OCCN3C=C(N4[C@H](C(F)F)COC4=O)N=C3C2=CC=1)C

Sicherheit

GDC-0077 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Inavolisib, or GDC-0077, is a potent and selective PI3K inhibitor. GDC-0077 blocks an enzyme involved in cancer growth called PI3K. GDC0077 binds to and inhibits various members of the PI3K family, including activating mutations in the catalytic alpha isoform PIK3CA. PI3K inhibition prevents the activation of the PI3K-mediated signaling pathway and inhibits the growth and survival of PI3K-overexpressing tumor cells. The IUPAC name of this compound is (S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)propanamide.

GDC-0077 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


GDC-0077 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 76)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581
sales@chemhifuture.com China 3135 58
Hubei Chuchang Biotech Co., Ltd.
+undefined15623860702
info@chuchangbiotech.com China 203 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32956 60
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830
figo.gao@foxmail.com China 8497 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695
laboratory@coreychem.com China 30236 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471
sales@sarms4muscle.com China 10473 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525
masar@topule.com China 8467 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58

2060571-02-8()Verwandte Suche:


  • GDC-0077
  • Inavolisib
  • Propanamide, 2-[[2-[(4S)-4-(difluoromethyl)-2-oxo-3-oxazolidinyl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]amino]-, (2S)-
  • (2S)-2-[[2-[(4S)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]amino]propanamide
  • GDC-0077; RG 6114; RO 7113755
  • RO 7113755
  • RG 6114
  • CPD1573
  • Inavolisib (GDC-0077)
  • GDC-0077 Inavolisib
  • Apoptosis,RG 6114,RG-6114,Phosphoinositide 3-kinase,Inhibitor,PI3K,Inavolisib,GDC 0077,GDC0077,inhibit
  • (S)-2-[[2-[(S)-4-(Difluoromethyl)-2-oxo-3-oxazolidinyl]-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl]amino]propanamide
  • Inavolisib (Synonyms: GDC-0077
  • (S)-2-((2-((S)-4-(Difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)propanamide
  • Inavolisib (RG-6114, RO-7113755)
  • (S)-2-((2-((S)-4-(Difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)propanamide , Inavolisib
  • 2060571-02-8
  • GDC-0077
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